Evidence map›Paper›PMID 42141865›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2026

Seasonality and effects of climatic exposures on community-acquired Legionnaires' disease incidence, Italy, 2005 to 2023.

Antonio Sciurti, Jessica Iera, Andrea Cannone, Alberto Mateo-Urdiales, Luigi De Angelis, Valentina Baccolini, Roberta Urciuoli, Stefania Giannitelli, Giulia Fadda, Benedetta Bellini and 6 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Letter to the editor: Seasonality and effects of climatic exposures on community-acquired Legionnaires' disease incidence, Italy, 2005 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Antonio SciurtiDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Jessica IeraDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Andrea CannoneDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Alberto Mateo-UrdialesDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Luigi De AngelisDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Valentina BaccoliniDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Roberta UrciuoliDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Stefania GiannitelliDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Giulia FaddaDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Benedetta BelliniDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Fabiola ManciniESCMID Study Group for Legionella Infections (ESGLI), Basel, Switzerland.
Maria ScaturroESCMID Study Group for Legionella Infections (ESGLI), Basel, Switzerland.
Maria Cristina RotaDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Maria Luisa RicciESCMID Study Group for Legionella Infections (ESGLI), Basel, Switzerland.
Antonino BellaDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Patrizio PezzottiDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUNDCommunity-acquired Legionnaires' disease (LD) has increased globally, including Europe. Climatic exposures may contribute to this rise, yet evidence from high-incidence countries, such as Italy, is limited.AIMWe aimed to assess LD seasonality at the national level and the effects of temperature, relative humidity and precipitation on LD incidence at the municipality level.METHODSWe analysed data on notified community-acquired LD cases and national climatic data from 2005 to 2023. Seasonality was assessed (peak-to-trough ratio (PTR)). A case time-series design with distributed lag nonlinear models was applied to estimate 1-10 week lagged effects of climatic exposures on LD incidence at the municipality level, as incidence rate ratios (IRRs).RESULTSOf the 28,662 notified LD cases, 27,458 (95.8%) were included. A clear seasonality was observed in the incidence, with a trough in early spring and a peak in autumn (PTR = 3.62; 95% confidence interval (CI): 2.45-5.34). Higher temperature and relative humidity had the strongest effects 10-9 weeks before disease onset (for 5°C increase above 15°C: IRR = 1.45; 95% CI: 1.33-1.58 and for 5% increase above 60%: IRR = 1.19; 95% CI: 1.12-1.26). Precipitation showed more immediate effects, particularly with a 1-week lag (for 5 mm increase above 10 mm: IRR = 1.07; 95% CI: 1.06-1.09). Findings were consistent among individuals aged ≥ 60 years.CONCLUSIONA clear seasonal pattern was seen in the LD incidence, peaking in summer and autumn. Temperature and humidity increased LD risk over longer lags, while precipitation had shorter-term effects, suggesting climatic exposures influence environmental proliferation and immediate transmission of

Indexed as

ClimateCommunity-Acquired InfectionsLegionella pneumophilaLegionnaires' DiseaseSeasonsAdolescentAdultAgedEnvironmental ExposureFemaleHumansHumidityIncidenceItalyMaleMiddle Agedcase time-seriesclimatehumidityLegionellaLegionnaires’ diseaserainfallsurveillancetemperature

Identifiers

PMID42141865
PMCPMC13074369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.