Evidence map›Paper›PMID 42141757›Full record

ArticleGut microbes2026

Antibiotic-associated

Fons F van den Berg, Hannah S Pauw, Hester C Timmerhuis, Marc G Besselink, Yama Issa, Marco J Bruno, Pieter Jan de Jonge, Harry van Goor, Erwin J M van Geenen, Rutger Quispel and 19 more

Abstract readMulticenter Study
In one paragraph

Article in Gut microbes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Fons F van den BergDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC Location AMC, Amsterdam, The Netherlands.ORCID 0000-0001-6494-4287
Hannah S PauwDepartment of Surgery, St Antonius Hospital, Nieuwegein, The Netherlands.
Hester C TimmerhuisDepartment of Surgery, St Antonius Hospital, Nieuwegein, The Netherlands.ORCID 0000-0001-5714-4951
Marc G BesselinkDepartment of Surgery, Amsterdam UMC Location AMC, Amsterdam, The Netherlands.ORCID 0000-0003-2650-9350
Yama IssaDepartment of Surgery, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-0191-8871
Marco J BrunoDepartment of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands.ORCID 0000-0001-9181-5499
Pieter Jan de JongeDepartment of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands.
Harry van GoorDepartment of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0003-0323-4876
Erwin J M van GeenenDepartment of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, The Netherlands.
Rutger QuispelDepartment of Gastroenterology and Hepatology, Reinier de Graaf Hospital, Delft, The Netherlands.
Wim van de VrieDepartment of Gastroenterology, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
Adriaan TanDepartment of Gastroenterology, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.ORCID 0000-0002-7389-5437
Muhammed HadithiDepartment of Gastroenterology and Hepatology, Maasstad Hospital, Rotterdam, The Netherlands.
Niels G VennemanDepartment of Gastroenterology and Hepatology, Medisch Spectrum Twente, Enschede, The Netherlands.ORCID 0000-0002-9418-057X
Rogier P VoermansAmsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, Amsterdam, The Netherlands.ORCID 0000-0002-9969-019X
Jeroen M JansenDepartment of Gastroenterology, OLVG, Amsterdam, The Netherlands.
Ben J WittemanDepartment of Gastroenterology and Hepatology, Gelderse Vallei Hospital, Ede, The Netherlands.ORCID 0000-0002-1341-8540
Matthijs P SchwartzDepartment of Internal Medicine and Gastroenterology, Meander Medical Center, Amersfoort, The Netherlands.ORCID 0000-0003-3106-3373
Roy L J van WanrooijAmsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, Amsterdam, The Netherlands.ORCID 0000-0003-0477-4532
Alexander C PoenDepartment of Gastroenterology and Hepatology, Isala, Zwolle, The Netherlands.
Peter van DuijvendijkDepartment of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-0441-6180
Marie-Paule AntenDepartment of Gastroenterology, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands.
Tessa E H RömkensDepartment of Gastroenterology and Hepatology, Jeroen Bosch Hospital, Hertogenbosch, The Netherlands.
Elske SieswerdaEuropean Clinical Research Alliance on Infectious Diseases (ECRAID), Utrecht, The Netherlands.ORCID 0000-0001-5819-4918
Merel M TielemansDepartment of Gastroenterology and Hepatology, Bravis Hospital, Roosendaal, The Netherlands.
Jeanin E van HooftDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-4424-0079
Marja A BoermeesterDepartment of Surgery, Amsterdam UMC Location AMC, Amsterdam, The Netherlands.ORCID 0000-0003-3890-8105
Robert C VerdonkDepartment of Gastroenterology and Hepatology, St Antonius Hospital, Nieuwegein, The Netherlands.ORCID 0000-0001-5591-0499
Hjalmar C van SantvoortDepartment of Surgery, St Antonius Hospital, Nieuwegein, The Netherlands.ORCID 0009-0007-1218-2883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infected pancreatic necrosis complicates 30% of necrotizing pancreatitis cases, with intestinal bacterial translocation as the presumed mechanism. To characterize gastrointestinal microbiota dynamics preceding infection, we performed a predefined subgroup analysis of the POEMA cohort, a prospective multicenter microbiota study across 20 Dutch hospitals. Of 276 patients with acute pancreatitis, 57 with necrotizing pancreatitis underwent twice-weekly rectal and salivary sampling for 30 d, analyzed using 16S rRNA sequencing. Twenty (35%) developed infected necrosis. After adjustment for baseline disease severity, biliary etiology, and prior antibiotic exposure, gastrointestinal

Indexed as

Anti-Bacterial AgentsEnterococcusGastrointestinal MicrobiomeGastrointestinal TractPancreatitis, Acute NecrotizingAdultAgedFemaleHumansMaleMiddle AgedNecrosisProspective StudiesRNA, Ribosomal, 16SSalivaAnti-Bacterial AgentsRNA, Ribosomal, 16SIntestinal colonizationintestinal microbiotanecrotizing pancreatitis

Identifiers

PMID42141757
PMCPMC13182963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.