Evidence map›Paper›PMID 42141702›Full record

SynthesisWound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

Does Antibiotic Treatment Before Bone Biopsy Affects the Identification of Bacterial Pathogens From Bone Culture in Diabetic Foot Osteomyelitis? A Systematic Review and Meta Analysis.

Lawrence A Lavery, Arthur N Tarricone, Andrew William Ernest Madsen, Nitish Thirugnanasambandam, Allen Gee, Dane K Wukich, Edgar J G Peters

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lawrence A LaveryDepartment of Orthopedic Surgery, The University of Texas Health Science Center, San Antonio, Texas, USA.
Arthur N TarriconeDepartment of Orthopedic Surgery, The University of Texas Health Science Center, San Antonio, Texas, USA.ORCID https://orcid.org/0000-0001-5311-6283
Andrew William Ernest MadsenDepartment of Medicine, Long School of Medicine at University of Texas San Antonion, San Antonio, Texas, USA.
Nitish ThirugnanasambandamDepartment of Orthopedic Surgery, The University of Texas Health Science Center, San Antonio, Texas, USA.ORCID https://orcid.org/0009-0007-3519-9987
Allen GeeDepartment of Medicine, Mount Sinai Morningside Hospital, New York, New York, USA.
Dane K WukichDepartment of Prosthetics and Orthotics, UT Southwestern School of Health Professions, Dallas Texas and Department of Orthopaedic Surgery UT Southwestern Medical Center, Dallas, Texas, USA.
Edgar J G PetersDepartment of Internal Medicine, VU University Medical Center, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our aim was to evaluate the effect of pre-biopsy antibiotics and bacterial pathogen recovery after bone biopsy in patients suspected of having diabetic foot osteomyelitis. A meta-analysis following PRISMA guidelines was conducted. Pubmed, EMBASE, and Cochrane Library were searched for comparative studies reporting positive culture outcomes stratified by antibiotic exposure prior to bone biopsy. Eligible studies included adult patients undergoing bone biopsy with extractable data on pre-biopsy antibiotic use and culture positivity. Pooled odds ratios were calculated using a random-effects model with the Mantel-Haenszel method. Statistical heterogeneity was assessed using the I

Indexed as

Anti-Bacterial AgentsBone and BonesDiabetic FootOsteomyelitisBiopsyHumansAnti-Bacterial Agentsantibioticsdiabetesfoot ulcerinfectionosteomyelitis

Identifiers

PMID42141702
PMCPMC13179428

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.