Evidence map›Paper›PMID 42141465›Full record

ReviewBMC oral health2026

Spontaneous bone formation after sinus graft infection control: a case report and review of the literature.

Jiaxin Luo, Shengyuan Wang, Xingchao Zeng, Fuchun Chen, Shiyong Zhao

Abstract readCase ReportsReview
In one paragraph

Review in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiaxin LuoDepartment of Oral Implantology, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction & Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou, Guangdong, 510182, China.
Shengyuan WangMedicine and Technology College of Zunyi Medical University, Zunyi, Guizhou, 563000, China.
Xingchao ZengDepartment of Oral Implantology, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction & Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou, Guangdong, 510182, China.
Fuchun ChenDepartment of Oral Implantology, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction & Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou, Guangdong, 510182, China.
Shiyong ZhaoDepartment of Oral Implantology, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction & Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou, Guangdong, 510182, China. syzhao@gzhmu.edu.cn.

Funding

Guangzhou Medical University Research Capacity Enhancement Program 2024SRP151Medical Scientific Research Foundation of Guangdong Province A2022528
6 · The paper itself

Abstract

backgroundSpontaneous bone formation in the maxillary sinus is a rare phenomenon, commonly attributed to multiple factors that influence the space between the sinus floor and mucosa, thereby promoting the formation of blood clots in this region. Nevertheless, these factors are not yet fully elucidated. CASE PRESENTATION: In January 2022, a 20-year-old male patient underwent bone-added osteotome sinus floor elevation with simultaneous implant placement at the maxillary left first molar. However, 10 days after surgery, the patient presented with left infraorbital pain, peri-implant suppuration, and a loose implant. Cone beam computed tomography (CBCT) images showed sinus opacification and reduced density of the peri-implant bone and graft materials. The implant and graft materials were then removed, and the socket was thoroughly irrigated with copious chlorhexidine solution and saline, then meticulously covered with iodoform gauze. The pain symptoms were alleviated a week after implant removal. The maxillary sinus remained opaque on CBCT images, with thinning of the lateral sinus wall and reduced bone height. After 3 months, clinical examination revealed no significant abnormalities in the soft tissues. Radiographic evaluations showed new bone formation within the maxillary sinus, accompanied by mucosal thickening and the disappearance of opacities. 2 years later, CBCT images displayed spontaneous bone formation in the maxillary sinus. Finally, an implant was placed, and the restoration was completed successfully.

conclusionsThis case report underscores the occurrence of spontaneous bone formation in the maxillary sinus after resolution of a postoperative sinus graft infection, ultimately enabling successful reimplantation at the same site. In analogous cases, prolonging the healing period may be beneficial to promote natural self-healing.

Indexed as

Maxillary SinusOsteogenesisSinus Floor AugmentationSurgical Wound InfectionBone TransplantationCone-Beam Computed TomographyHumansMaleYoung AdultBlood clotCase reportMaxillary sinus floor elevationSinus graft infectionSpontaneous osteogenesis

Identifiers

PMID42141465
PMCPMC13383440

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.