Evidence map›Paper›PMID 42141413›Full record

ArticleBMC oral health2026

Influence of varying oral pH conditions on the material stability of thermoplastic orthodontic aligners: an in vitro study.

Dhruv Ahuja, Bhawna Negi, Anjana Goyal, Puneet Batra, Ashith Mv, Kumar Rakshak Anand, Khushi Gupta, Bhoomi Pitanjali Singh, Areeba Parvez

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In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dhruv AhujaDepartment of Orthodontics and Dentofacial Orthopedics, Manav Rachna Dental College, Manav Rachna International Institute of Research and Studies (MRIIRS), Faridabad, Haryana, India.
Bhawna NegiManav Rachna Dental College, Manav Rachna International Institute of Research and Studies (MRIIRS), Faridabad, Haryana, India.
Anjana GoyalDepartment of Biochemistry, Manav Rachna Dental College, Manav Rachna International Institute of Research and Studies (MRIIRS), Faridabad, Haryana, India.
Puneet BatraDepartment of Orthodontics and Dentofacial Orthopedics, Manav Rachna Dental College, Manav Rachna International Institute of Research and Studies (MRIIRS), Faridabad, Haryana, India.
Ashith MvDepartment of Orthodontics and Dentofacial Orthopedics, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, 576014, India. ashith.mv@manipal.edu.
Kumar Rakshak AnandDepartment of Oral and Maxillofacial Surgery, Manav Rachna Dental College, Manav Rachna International Institute of Research and Studies (MRIIRS), Faridabad, Haryana, India.
Khushi GuptaDepartment of Orthodontics and Dentofacial Orthopedics, Manav Rachna Dental College, Manav Rachna International Institute of Research and Studies (MRIIRS), Faridabad, Haryana, India.
Bhoomi Pitanjali SinghManav Rachna Dental College, Manav Rachna International Institute of Research and Studies (MRIIRS), Faridabad, Haryana, India.
Areeba ParvezManav Rachna Dental College, Manav Rachna International Institute of Research and Studies (MRIIRS), Faridabad, Haryana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClear thermoplastic orthodontic aligners are widely used due to their aesthetic appeal and patient comfort; however, exposure to chemically diverse intraoral environments may compromise their physical, aesthetic, and chemical stability. This study aimed to evaluate the effect of acidic, alkaline, and neutral chemical environments on weight variation, pH interaction, colour stability, and leaching behaviour of thermoplastic orthodontic aligner materials.

methodsThirty maxillary thermoplastic orthodontic aligners representing three commercial materials (Erkodur, Duran, and Zendura) were immersed in acidic (lime juice), alkaline (ENO

resultsAligners in acidic media exhibited the greatest weight reduction (3.410 ± 0.015 g to 3.358 ± 0.025 g; p < 0.001), followed by alkaline media. Colour change was highest in acidic conditions (ΔE = 3.08 ± 0.15), moderate in alkaline (1.92 ± 0.12), and minimal in neutral media (0.77 ± 0.08). Leaching absorbance was significantly higher in acidic media at Day 14 (0.083 ± 0.004 AU; p < 0.001).

conclusionOral chemical exposures significantly compromise the physicochemical and aesthetic properties of thermoplastic aligners, highlighting the need for careful material selection, patient guidance, and further in vivo studies to confirm clinical impact.

Indexed as

Orthodontic Appliances, RemovableColorHumansHydrogen-Ion ConcentrationIn Vitro TechniquesMaterials TestingSaliva, ArtificialSaliva, ArtificialChemical exposureClear alignersColour stabilityIn vitro studyLeachingThermoplastic polymers

Identifiers

PMID42141413
PMCPMC13383513

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.