Evidence map›Paper›PMID 42141296›Full record

ArticleDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2026

Medication discrepancies and medication-related problems in psychiatric patients: A medication reconciliation study.

Mozhdeh Shahabi, Mahsa Panahishokouh, Niayesh Mohebbi

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Article in Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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3 authors.

Mozhdeh ShahabiSchool of Pharmacy, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Mahsa PanahishokouhDepartment of Clinical Pharmacy, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran.ORCID http://orcid.org/0000-0002-9648-2651
Niayesh MohebbiDepartment of Clinical Pharmacy, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran. nmohebbi@sina.tums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedication discrepancies (MDs) are common medication errors that can lead to adverse drug events (ADEs) and suboptimal treatment. Medication reconciliation (MR) programs are implemented in many countries, including Iran, to identify, resolve, and prevent MDs and other medication-related problems (MRPs). In the psychiatric setting, the importance of identifying and addressing MRPs is even greater due to the high prevalence of polypharmacy, limited patient cooperation, and other factors. This study aimed to comprehensively investigate the prevalence of MDs and MRPs in psychiatric patients.

methodsThis study included 302 psychiatric patients receiving at least two systemic medications daily. Their medications were reviewed at discharge using the Pharmaceutical Society of Australia (PSA) guidelines to identify MRPs. The collected data were analyzed statistically.

resultsIn this study, patients were taking a total of 1421 medications (4.71 medications per patient). A total of 493 MDs and 392 MRPs were identified. The most common MRPs were, in decreasing order, medication underuse or non-adherence by the patient (175 cases, 44.64% of all MRPs) and drug interactions (168 cases, 42.85%). The number of drug interactions significantly increased with the increasing number of underlying diseases and the number of medications used (P < 0.001 in both cases).

conclusionThe findings of this study indicate a high prevalence of medication-related problems (MRPs) in psychiatric settings, highlighting the critical role of MR programs in mitigating such risks. Among the challenges identified, non-adherence to treatment and potential drug interactions emerged as the most significant issues affecting psychiatric patients.

Indexed as

Drug-Related Side Effects and Adverse ReactionsMedication ErrorsMedication ReconciliationMental DisordersAdultAgedDrug InteractionsFemaleHumansIranMaleMiddle AgedPolypharmacyPsychotropic DrugsYoung AdultPsychotropic DrugsMedication discrepancyMedication reconciliationPsychiatric disorderPsychotropic medication

Identifiers

PMID42141296
PMCPMC13179390

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