ReviewAnnals of biomedical engineering2026
Unveiling the Clinical Impact of Lower Limb Robotic Devices in Neurorehabilitation: An Umbrella Review.
Review in Annals of biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Neurorehabilitation for cognitive and motor recovery: mechanisms, interventions, and translational advances.Frontiers in neurology · 2026Review
- Baseline PTSD and depressive symptoms predict multidimensional recovery after combat-related transtibial amputation: a prospective cohort study.Frontiers in rehabilitation sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis umbrella review aimed to assess the effectiveness of lower extremity robotic devices in clinical settings by analyzing motor and non-motor rehabilitation outcomes across different neurological conditions, including stroke, spinal cord injury, multiple sclerosis, and Parkinson's disease.
methodsA systematic search of literature published in English over the past twelve years was conducted using four major databases (PubMed, Scopus, Cochrane Library, and Web of Science). The search focused on reviews addressing the use of lower-limb robotic devices in patients with neurological diseases. Only reviews that followed standardized protocols and reported quantitative motor and/or non-motor rehabilitation outcomes were included. Extracted information included demographic characteristics, experimental procedures, and numerical outcomes related to motor and non-motor functions (e.g., walking test scores, clinical scale ratings).
resultsA total of 33 reviews met the inclusion criteria. Stroke was the most frequently studied condition, whereas Parkinson's disease and multiple sclerosis were rarely addressed. Findings related to stroke suggested that robotic rehabilitation may provide benefits over conventional therapy, with statistically significant improvements in some cases. In contrast, evidence for spinal cord injury, Parkinson's disease, and multiple sclerosis was limited and inconsistent.
conclusionsOverall, lower-limb robotic devices show promise in neurorehabilitation, particularly for post-stroke recovery. However, further research is required to standardize intervention protocols, assess cost-effectiveness, and better understand patient and therapist experiences to support broader clinical adoption.
Indexed as
Identifiers
42141217What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.