Evidence map›Paper›PMID 42141114›Full record

ArticleEuropean journal of human genetics : EJHG2026

From clinical genetics to genomic-based public health screening programmes: duty-based ethics as a guide for responsible implementation.

Helena Carley, Ingrid Slade

Abstract read
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In one paragraph

Article in European journal of human genetics : EJHG, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Helena CarleySouth East Thames Regional Genetics Service, Guy's & St Thomas NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0002-5762-2842
Ingrid SladeCentre for Population Health Sciences, School of Primary Care, Population Health and Medical Education, Faculty of Medicine, University of Southampton, Southampton, UK. I.H.Slade@soton.ac.uk.ORCID http://orcid.org/0009-0005-4946-8688

Funding

Wellcome Trust (Wellcome) 200314/Z/15/Z
6 · The paper itself

Abstract

A renewed focus on disease prevention has placed genomics firmly in the spotlight. Policymakers and health services across Europe are considering ways to facilitate disease prevention and early disease detection through population-level initiatives such as newborn genomic screening and polygenic risk scores. This commentary explores, through the lens of duty-based ethics, the ethical considerations in the design of genomic screening programmes. As genomic medicine becomes embedded in public health strategies, a robust ethical framework is essential to ensure that its promises are realised equitably and responsibly.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.