Evidence map›Paper›PMID 42141006›Full record

ArticleNPJ primary care respiratory medicine2026

Patient perspectives of asthma treatment and belief barriers to implementing new guidelines: a qualitative analysis of an online forum.

Zoe Moon, Hannah Truscott, Grainne d' Ancona, Anna De Simoni, Louise Fleming, Mark L Levy, Aziz Sheikh, Robert Horne

Abstract read
In one paragraph

Article in NPJ primary care respiratory medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zoe MoonCentre for Behavioural Medicine, University College London, London, UK.
Hannah TruscottUniversity of Leeds, Leeds, UK.
Grainne d' AnconaGuy's and St Thomas' NHS Foundation Trust, London, UK.
Anna De SimoniQueen Mary University London, London, UK.
Louise FlemingRoyal Brompton Hospital, Imperial College, London, London, UK.
Mark L LevySemi-Retired General Practitioner, London, UK.
Aziz SheikhNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Robert HorneCentre for Behavioural Medicine, University College London, London, UK. r.horne@ucl.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For the last 40 years, the first line of asthma treatment has been short-acting beta2 agonists (SABA) used as symptom relief alongside daily inhaled corticosteroids (ICS) as preventers. New guidelines recommend replacing SABA relievers with ICS-based relievers (ICS-formoterol) because of clear risks from excess and sole use of SABA. This study aimed to explore patient perceptions of SABA, ICS and ICS-formoterol, with a focus on identifying barriers to adherence to new recommended treatments. A qualitative study was carried out investigating UK asthma online community forum posts using keyword searches between July 2021 and March 2025. Inductive thematic analysis was used to analyze the data, informed by the Necessity Concerns Framework. 326 posts were identified across 206 adults with asthma. Thematic analysis highlighted that many people remained attached to their SABA and viewed it as a key element of their treatment. They appeared unconvinced by warnings around SABA over-use and were dissatisfied with the quality of advice from health care professionals (HCPs). In contrast, they raised a range of concerns about ICS and ICS-formoterol, and had reservations about replacing SABA with these treatments. A common objection to replacing SABA was that ICS-formoterol does not provide the same symptom relief. Results highlight a perceived lack of individualized care from HCPs and insufficient explanation and justification of treatment changes. This analysis highlights several potential barriers to adherence to recommended asthma treatment. Strategies to support the implementation of asthma treatment guidelines should include addressing patients' treatment beliefs and educating clinicians to better communicate treatment changes.

Indexed as

Adrenergic beta-2 Receptor AgonistsAnti-Asthmatic AgentsAsthmaGuideline AdherenceAdministration, InhalationAdrenal Cortex HormonesAdultFemaleFormoterol FumarateHumansInternetMalePractice Guidelines as TopicQualitative ResearchUnited KingdomAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsAnti-Asthmatic AgentsFormoterol Fumarate

Identifiers

PMID42141006
PMCPMC13424341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.