Evidence map›Paper›PMID 42140831›Full record

ArticleUltrasound in medicine & biology2026

A Magnetic Resonance-Compatible Fiberoptic Temperature Sensor for Measuring Focused Ultrasound-Induced Heating Without Artifacts.

Sara L Johnson, Henrik Odéen, Harry Vine, Patricia Guenkawa, Benjamin Nelson, Allison Payne

Abstract read
In one paragraph

Article in Ultrasound in medicine & biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sara L JohnsonRadiology & Imaging Sciences, University of Utah, Salt Lake City, UT, USA.
Henrik OdéenRadiology & Imaging Sciences, University of Utah, Salt Lake City, UT, USA.
Harry VineOSENSA Innovations, Burnaby BC, Canada.
Patricia GuenkawaBiomedical Engineering, University of Utah, Salt Lake City, UT, USA.
Benjamin NelsonSchool of Computing, University of Utah, Salt Lake City, UT, USA.
Allison PayneRadiology & Imaging Sciences, University of Utah, Salt Lake City, UT, USA. Electronic address: allison.payne@hsc.utah.edu.

Funding

Validation and translation of a non-invasive, MR-guided breast cancer therapyR37CA224141 · NCI · UNIVERSITY OF UTAH · PI PAYNE, ALLISON · 2018 to 2024
$3.7M
A tissue viability imaging biomarker for use in non-invasive breast cancer therapyR01CA259686 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI SARANG JOSHI, Allison Payne · 2022 to 2026
$2.9M
Siemens MAGNETOM Prisma 3T MRI scannerS10OD018482 · OD · UNIVERSITY OF UTAH · PI PARKER, DENNIS L · 2015 to 2015
$1.2M
NCI NIH HHS R01 CA259686NCI NIH HHS R37 CA224141NIH HHS S10 OD018482
6 · The paper itself

Abstract

objectiveThis work evaluated a fiberoptic probe that meets all features and qualities that render it highly suitable for validating magnetic resonance temperature imaging measurements for magnetic resonance-guided focused ultrasound (MRgFUS) applications. The fiberoptic probe performance was compared with other probes with viscous heating artifact (VHA) effects in both a free-field and a controlled tissue-mimicking phantom environment with MRgFUS heating applied.

methodsThree fiberoptic probes with different coatings (nylon, ethylene tetrafluoroethylene and polyimide) and tip diameters (1, 0.75 and 0.14 mm) were evaluated in free-field and tissue-mimicking phantom environments at 1 and 3 MHz under a variety of acoustic intensity and probe incidence angles with respect to the acoustic field. Concurrently acquired temperature measurements from the fiberoptic probes and magnetic resonance temperature imaging were compared, with Bland-Altman analysis also performed.

resultsThe 0.14 mm diameter fiberoptic probe composed of a glass optical fiber and ethylene tetrafluoroethylene coating had negligible VHAs under all acoustic exposure conditions. Comparison of the magnetic resonance temperature imaging and fiberoptic temperature data resulted in a root mean squared error of 0.52°C and 0.47°C and a limit of agreement of 1.2°C and 1.0°C when tested in a 1 and 3 MHz acoustic field, respectively. This contrasts with the results from a 1 mm-diameter fiberoptic probe composed of a polymer optical fiber with a nylon coating that demonstrated a root mean squared error and limit of agreement of 15°C and 3.5°C, and 37°C and 7.5°C at 1 and 3 MHz, respectively.

conclusionThe thin-diameter (0.14 mm) glass fiberoptic probe monitored focused ultrasound-induced heating in the acoustic field without evidence of a VHA. The ability to perform calibration and accuracy studies in an active acoustic field will broaden the range of testing allowed, improving the calibration range of magnetic resonance imaging temperature sequences.

Indexed as

Fiber Optic TechnologyHigh-Intensity Focused Ultrasound AblationMagnetic Resonance ImagingArtifactsEquipment DesignHot TemperaturePhantoms, ImagingFiberoptic temperature probesFocused ultrasoundMRI temperature imagingMR thermometryTemperature measurement validation

Identifiers

PMID42140831
PMCPMC13339831

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.