Evidence map›Paper›PMID 42139647›Full record

ArticleJCO clinical cancer informatics2026

Interactive Medication Calendars to Support At-Home Care of Pediatric Patients With ALL.

Lydia Haupt Levy, Clara C Hatch, Rachel Selig, Carly Orpik, Anna C Revette, Justine Kahn, Katie A Greenzang

Abstract read
In one paragraph

Article in JCO clinical cancer informatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Development and pre-testing of a family-centered digital intervention to help families know what to EXPECT from pediatric acute lymphoblastic leukemia therapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lydia Haupt LevyDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA.ORCID 0009-0003-7761-3980
Clara C HatchDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA.
Rachel SeligDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA.
Carly OrpikDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA.
Anna C RevetteDivision of Population Sciences, Dana-Farber Cancer Institute, Boston, MA.ORCID 0000-0002-4590-755X
Justine KahnDepartment of Pediatrics, Columbia University Medical Center, New York, NY.ORCID 0000-0003-3330-6754
Katie A GreenzangDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA.ORCID 0000-0002-7591-2245

Funding

Expectations for Pediatric Cancer Treatment (EXPECT): A Family-Centered Intervention to Prepare Parents for Pediatric Leukemia TherapyK08CA245036 · NCI · DANA-FARBER CANCER INST · PI GREENZANG, KATIE A. · 2019 to 2023
$761k
NCI NIH HHS K08 CA245036
6 · The paper itself

Abstract

purposePediatric ALL, the most common childhood cancer, requires complex, multiyear treatment. Most treatment occurs in the outpatient setting, and families must manage and administer chemotherapy and supportive care medications at home. Many parents feel overwhelmed by medication quantities, varied administration methods, and complex schedules, collectively contributing to high caregiver burden and medication errors. Strategies to support families in at-home medication administration are needed.

methodsUsing a 2-phase user-centered design process, we developed and pretested interactive medication calendars to support pediatric ALL treatment on Dana-Farber Cancer Institute ALL Consortium trials. In phase I, secondary qualitative analyses of interviews with patients, families, and health care providers revealed desired components and functionality to support ALL treatment management. A multidisciplinary steering committee oversaw the cocreation of medication calendars with a subcommittee of health care providers, a graphic designer, and digital-health specialists. In phase II, calendars were pretested with families.

resultsAnalyses revealed desires for a big-picture treatment overview alongside phase-specific information and risk group-based resources. Medication calendars were developed to be available digitally via password-protected website. Calendars include treatment cycle-length overviews, individual medications, administration schedule and frequency, and icons denoting administration mode (eg, oral, intrathecal). Hyperlinked teaching sheets describe drug-specific side effects and toxicities, letting families choose information detail. Providers can also print calendars for patient-specific annotation to support at-home care. In pretesting, parents welcomed personalized calendars and said they would rely on them for at-home administration.

conclusionInteractive medication calendars may improve family self-management through supporting medication administration across risk groups and treatment phases. Calendars are included in a family-centered digital intervention to improve pediatric ALL therapy communication, which will be pilot-tested to assess feasibility and outcomes.

Indexed as

Home Care ServicesPrecursor Cell Lymphoblastic Leukemia-LymphomaCaregiversChildChild, PreschoolFemaleHumansMale

Identifiers

PMID42139647
PMCPMC13524202

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.