Evidence map›Paper›PMID 42139639›Full record

ArticleNeurology2026

Pearls & Oy-Sters: Plantar Agraphesthesia in Corticobasal Syndrome.

Jonathan Arthur Perkins, Raymond S Price, Joaquin A Vizcarra

Abstract readCase Reports
In one paragraph

Article in Neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jonathan Arthur PerkinsFrom the Department of Neurology, University of Pennsylvania, Philadelphia.ORCID 0009-0006-9170-731X
Raymond S PriceFrom the Department of Neurology, University of Pennsylvania, Philadelphia.ORCID 0000-0002-7907-0321
Joaquin A VizcarraFrom the Department of Neurology, University of Pennsylvania, Philadelphia.ORCID 0000-0003-0306-4774

Funding

Training Program in Neuroengineering and MedicineT32NS091006 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Brian Litt · 2015 to 2026
$4.1M
NINDS NIH HHS T32 NS091006
6 · The paper itself

Abstract

We describe a 70-year-old man with no significant medical history who developed progressive left leg numbness, gait dysfunction, and recurrent falls. Within a year, he reported difficulty with both initiating steps and perceiving his left leg as his own. Neurologic evaluation revealed foot dystonia, bradykinesia, and plantar agraphesthesia. Electromyography and nerve conduction studies were unremarkable. Brain MRI demonstrated asymmetric parietal atrophy, greatest on the right. His symptoms did not improve with high-dose carbidopa-levodopa (900 mg/day). This case highlights plantar agraphesthesia as a valuable bedside sign of lower limb cortical sensory loss, even in the absence of hand involvement.

Indexed as

Corticobasal DegenerationAgedCarbidopaDrug CombinationsHumansLevodopaMagnetic Resonance ImagingMaleCarbidopacarbidopa, levodopa drug combinationDrug CombinationsLevodopa

Identifiers

PMID42139639
PMCPMC13182979

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.