Evidence map›Paper›PMID 42139234›Full record

ArticleJournal of natural products2026

Cell-Free Synthesis of Cannabistilbene I: A Dual Acting Anti-Inflammatory from

Kelly F Boddington, Eric Soubeyrand, Kristen Van Gelder, Colby Perrin, Taylor J B Forrester, Jennifer Holborn, José A Casaretto, M Sameer Al-Abdul-Wahid, Mathew L Piotrowski, Jakob Magolan and 4 more

Abstract read
In one paragraph

Article in Journal of natural products, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kelly F BoddingtonDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.ORCID 0000-0002-7880-5293
Eric SoubeyrandDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.ORCID 0000-0003-2970-3183
Kristen Van GelderDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Colby PerrinDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Taylor J B ForresterDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.ORCID 0000-0002-5609-1453
Jennifer HolbornDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
José A CasarettoDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
M Sameer Al-Abdul-WahidNMR Centre, University of Guelph, Guelph, Ontario N1G 2W1, Canada.ORCID 0000-0001-7925-5863
Mathew L PiotrowskiDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario L8S 4L8, Canada.
Jakob MagolanDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario L8S 4L8, Canada.ORCID 0000-0002-2947-8580
Jasmin LalondeDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.ORCID 0000-0002-6797-1894
Matthew S KimberDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.ORCID 0000-0001-9454-5586
Steven J RothsteinDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Tariq A AkhtarDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.ORCID 0000-0002-6492-681X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the potential of Cannabis bibenzyls to remedy acute and chronic inflammation, their relative scarcity, in planta, has hindered applications for them in mainstream therapeutic efforts. Here, we describe the biocatalytic synthesis of cannabistilbene I (

Indexed as

Anti-Inflammatory AgentsCannabisStilbenesMethyltransferasesMolecular StructureResveratrolStreptomycesAnti-Inflammatory AgentsMethyltransferasesResveratrolStilbenes

Identifiers

PMID42139234
PMCPMC13316989

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.