← GIP/GLP-1 & amylin agonists × body weight & composition

TrialJAMA dermatology2026

Ixekizumab With or Without Tirzepatide in Adults With Psoriasis and Overweight or Obesity: A Phase 3b Randomized Clinical Trial.

Mark Lebwohl et al.PubMed ↗Full text ↗Publisher ↗

The primary results report of NCT06588283.

What the trial testedas reported · 2026

Not counted

Probably raised body weight & composition

+21.2percentage points+12.8 to +29.7

As reported

difference 21.2 %, 95% CI 12.8–29.7

One number in the abstract

the abstract, start to end

… with ixekizumab (risk difference [RD], 21.2%; 95% CI, 12.8%-29.7%; …

← favours treatmentfavours comparator →
could be chance
Body weight & composition
21.212.8–29.7
GIP/GLP-1 & amylin agonistsBody weight & composition
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6 papers cite it

2026
this papercites it

The trial

Full record →Abstract, authors, funding and every citing paper · PMID 42139049