Evidence map›Paper›PMID 42138979›Full record

ArticleeLife2026

Tumors mimic the niche to inhibit neighboring stem cell differentiation.

Yang Zhang, Yuejia Wang, Jinqiao Song, Lizhong Yan, Ziguang Wang, Dongze Song, Haojun Wang, Sining Yang, Liyuan Niu, Chang Sun and 3 more

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yang ZhangDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Yuejia WangDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Jinqiao SongDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Lizhong YanDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Ziguang WangDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Dongze SongDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Haojun WangDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Sining YangDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Liyuan NiuDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Chang SunDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Hanning ZhangDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Yudi ZhaoDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.
Shaowei ZhaoDepartment of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin, China.ORCID https://orcid.org/0000-0002-4544-7215

Funding

National Natural Science Foundation of China 32070871National Natural Science Foundation of China 32270841
6 · The paper itself

Abstract

Although it is well established that stem cells maintain tissue homeostasis while tumors disrupt it, the mechanisms by which tumors influence the development of nearby stem cells remain poorly understood. Using

Indexed as

Cell DifferentiationDrosophila melanogasterStem Cell NicheStem CellsAnimalsBone Morphogenetic ProteinsDNA HelicasesDrosophila ProteinsFemaleOvarySignal Transductionbam protein, Drosophilabgcn protein, DrosophilaBone Morphogenetic ProteinsDNA Helicasesdpp protein, DrosophilaDrosophila ProteinsbamBMP signalingcancer biologydevelopmental biologyD. melanogastergermline stem cellstem cell nichetumors

Identifiers

PMID42138979
PMCPMC13179058

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.