ArticleRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2026
The triglyceride-glucose index can indicate lipid and atherogenic alterations in adolescents, regardless of excess weight.
Article in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Triglyceride-glucose index identifies early metabolic stress and β-cell vulnerability in pediatric obesity.World journal of pediatrics : WJP · 2026Article
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10 authors.
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Abstract
objectiveThe aim of this study was to evaluate the role of the triglyceride-glucose (TyG) index in identifying changes in lipid profile and atherogenic risk in adolescents, according to the presence or absence of excess weight.
methodsThis cross-sectional study included 823 students aged 10-18 years, classified as having or not having excess weight based on body mass index. Lipid profile was assessed and classified according to the guidelines of the Brazilian Society of Cardiology. Atherogenic risk was evaluated using the Castelli I and II indices, the Atherogenic Index of Plasma, and the atherogenic coefficient. The TyG index was assessed in tertiles. The association between TyG and lipid and atherogenic outcomes was analyzed using logistic and linear regression, stratified by excess weight status.
resultsElevated TyG was associated with altered total cholesterol (TC), high-density lipoproteincholesterol (HDL-c), low-density lipoprotein-cholesterol (LDL-c), and non-HDL-c in adolescents without excess weight (p<0.001), whereas in those with excess weight, this association was found only in TC and non-HDL-c. All atherogenic indices were positively associated with elevated TyG (p<0.001).
conclusionsAdolescents without excess weight showed clearer associations between TyG and lipid profile; however, atherogenic risk was directly associated with elevated TyG, regardless of the presence or absence of excess weight.
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