ArticlePediatric cardiology2026
Outcomes After Tetralogy of Fallot Repair with Preservation of Intact Pulmonary Valve Structure.
Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
The optimal post-repair pulmonary valve annulus (PVA) diameter in tetralogy of Fallot (TOF) may be far smaller than anticipated. Therefore, selected patients can undergo repair without manipulating the PV structure. Of the 347 patients who underwent TOF repair with PVA preservation (AP) from January 2016 to December 2023, 100 had AP while leaving the PV structure untouched. Median age, weight, and PVA (Z) at repair were 125 days (interquartile range [IQR], 96.5-167.5), 6.3 kg (IQR, 5.1-7.1), and -0.8 (IQR, -1.8 to 0.3), respectively. One non-cardiac late death occurred 9 months after repair. During a median 46.2 months follow-up, 14 patients (14%) required reinterventions for significant right ventricular outflow tract obstruction (RVOTO): balloon pulmonary valvuloplasty (BPV) in 6, surgical RVOTO relief in 4, and BPV followed by surgery in 4 (including 1 who received a right ventricle to pulmonary artery conduit to bypass a left anterior descending coronary artery crossing the RVOT). Except for the conduit recipient, only 2 patients showed significant RVOTO (n = 1) and significant pulmonary regurgitation (PR) (n = 1) at the last follow-up. On Cox regression, neonatal repair (hazard ratio [HR], 5.12, P = 0.02) and a higher P
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