Evidence map›Paper›PMID 42138705›Full record

ArticleApplied and environmental microbiology2026

Early supplemental feeding improves post-weaning growth restriction in lambs via the gastrointestinal-metabolic axis.

Lele Zhu, Mengmeng Wang, Xinyue Zhang, Tingting Dou, Heng Hua, Xinyue Tang, Xiaoyu Niu, Qifang Kou, Yulin Chen, Menghao Pan and 1 more

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lele ZhuCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.ORCID 0009-0000-5858-2523
Mengmeng WangCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.ORCID 0009-0000-4375-5313
Xinyue ZhangCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.ORCID 0009-0002-7664-2926
Tingting DouCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.ORCID 0009-0008-0331-9881
Heng HuaCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.ORCID 0009-0006-6167-2064
Xinyue TangCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.ORCID 0009-0002-9839-6930
Xiaoyu NiuWuzhong Hongsibao Tianyuan Fine-Breed Sheep Farming & Propagation Co., Ltd, Wuzhong, China.ORCID 0009-0000-5223-9011
Qifang KouWuzhong Hongsibao Tianyuan Fine-Breed Sheep Farming & Propagation Co., Ltd, Wuzhong, China.ORCID 0009-0004-9259-0198
Yulin ChenCollege of Animal Science and Technology, Northwest A&F University, Yangling, China.ORCID 0000-0001-5679-4055
Menghao PanCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.ORCID 0000-0003-2120-9754
Baohua MaCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.ORCID 0000-0002-8332-4275

Funding

the Special Project Program of the Department of Agriculture and Rural Affairs, Ningxia Hui Autonomous Region 2019 NXTS-001
6 · The paper itself

Abstract

The weaning period often induces growth restriction in lambs due to gastrointestinal immaturity and dietary transition. Although early supplemental feeding (ESF) shows promise, its systemic mechanisms via the rumen microbiota-gut-metabolism axis remain incompletely understood. Sixty Tan lambs were assigned to a control group (suckling only), Trial Group I (free-access ESF from 10 days), and Trial Group II (free-access + forced isolation from 15 days). Growth performance, rumen fermentation, intestinal morphology, serum metabolites, and rumen microbiota were comprehensively analyzed. The supplemental feeding regimen in Trial Group I significantly improved body weight, average daily gain, and body size before and after weaning. Rumen butyrate and acetate concentrations increased markedly, with enrichment of beneficial microbiota (

Indexed as

Animal FeedGastrointestinal MicrobiomeRumenAnimalsDietDietary SupplementsFermentationMaleSheepWeaningearly supplemental feedingintestinelambsmetabolismrumen microbiotaweaning-induced growth restriction

Identifiers

PMID42138705
PMCPMC13274353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.