Reverse Takotsubo Syndrome in Women During High Hormonal States Related to In Vitro Fertilization.

Alexander Y Lee, Siddharth Singh, Paul J Marano, Erica T Wang, Margareta D Pisarska, Janet Wei

Abstract readCase Reports

In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexander Y LeeDepartment of Internal Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Siddharth SinghDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Paul J MaranoDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Erica T WangDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Margareta D PisarskaDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Janet WeiDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA; Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA. Electronic address: Janet.Wei@cshs.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Takotsubo syndrome (TTS) has heterogenous clinical presentations for which the pathophysiologic mechanisms remain incompletely understood. Identifying patterns to the variants of TTS, including reverse TTS, may provide insight into TTS pathophysiology. In this report, we share 3 cases of reverse TTS in premenopausal women at different stages of in vitro fertilization, suggesting a link between heightened hormonal states and midbasal left ventricular dysfunction in the setting of TTS.

Indexed as

cardiomyopathyechocardiographypregnancy

Identifiers

PMID42138668

DOI10.1016/j.jaccas.2026.108349

PMCPMC13309686

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LicenceCC BY-NC-ND

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.