ArticleInfection and immunity2026
TusDCB-mediated tRNA sulfur modification is required for virulence and intestinal fitness in enterohemorrhagic
Yumika Sato, Kazutomo Suzue, Hideru Obinata, Mio Horinouchi, Ayako Takita, Mai Maruhashi, Yoji A Minamishima, Haruyoshi Tomita, Hidetada Hirakawa
Abstract read
In one paragraphArticle in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
9 authors.
Yumika SatoDepartment of Bacteriology, Graduate School of Medicine, Gunma University, Maebashi, Gunma, Japan.
Kazutomo SuzueDepartment of Infectious Diseases and Host Defense, Graduate School of Medicine, Gunma University, Maebashi, Gunma, Japan.
Hideru ObinataCore Facility Management and Technical Collaboration Center, Gunma University, Maebashi, Gunma, Japan.
Mio HorinouchiDepartment of Bacteriology, Graduate School of Medicine, Gunma University, Maebashi, Gunma, Japan.
Ayako TakitaDepartment of Bacteriology, Graduate School of Medicine, Gunma University, Maebashi, Gunma, Japan.
Mai MaruhashiDepartment of Bacteriology, Graduate School of Medicine, Gunma University, Maebashi, Gunma, Japan.
Yoji A MinamishimaCore Facility Management and Technical Collaboration Center, Gunma University, Maebashi, Gunma, Japan.ORCID 0000-0001-7995-9318 Haruyoshi TomitaDepartment of Bacteriology, Graduate School of Medicine, Gunma University, Maebashi, Gunma, Japan.ORCID 0000-0001-9969-2235 Hidetada HirakawaDepartment of Bacteriology, Graduate School of Medicine, Gunma University, Maebashi, Gunma, Japan.ORCID 0000-0002-9528-4012 Funding
Japan Agency for Medical Research and Development JP23gm1610013Japan Society for the Promotion of Science 23K24126, 24K22200
6 · The paper itselfAbstract
Sulfur modification of tRNAs enhances translational accuracy and efficiency, yet its contribution to bacterial pathogenesis remains poorly understood. In
Indexed as
Enterohemorrhagic Escherichia coliEscherichia coli InfectionsEscherichia coli ProteinsIntestinesRNA, TransferSulfurAnimalsCitrobacter rodentiumEnterobacteriaceae InfectionsGene Expression Regulation, BacterialMiceVirulenceEscherichia coli ProteinsRNA, TransferSulfurbacterial pathogenesisintestinal infectionshiga-toxin producing Escherichia colitRNA modificationtype III secretion systemvirulence
Identifiers
PMID42138637
PMCPMC13248664
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