Evidence map›Paper›PMID 42138343›Full record

ArticlePsycho-oncology2026

Development of Psychosocial Distress in Cancer Survivors and Its Potential Prognostic Impact on Survival: A Scoping Review.

Yifeng Gao, Chien-Tzu Lee, Melissa S Y Thong, Daniela Doege, Volker Arndt

Abstract readScoping Review
In one paragraph

Article in Psycho-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yifeng GaoCancer Survivorship Outcomes and Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID https://orcid.org/0000-0002-3838-990X
Chien-Tzu LeeCancer Survivorship Outcomes and Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Melissa S Y ThongCancer Survivorship Outcomes and Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID https://orcid.org/0000-0002-6987-705X
Daniela DoegeCancer Survivorship Outcomes and Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID https://orcid.org/0000-0002-7499-5376
Volker ArndtCancer Survivorship Outcomes and Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID https://orcid.org/0000-0001-9320-8684

Funding

Deutsches KrebsforschungszentrumGerman Academic Exchange Service 91897610
6 · The paper itself

Abstract

backgroundWhile single-point assessments of psychosocial distress have been associated with survival outcomes, investigations examining longitudinal changes in psychosocial distress and survival outcomes remain limited.

aimsThis scoping review evaluates existing literature on longitudinal distress patterns and their association with survival outcomes.

methodsA comprehensive search was performed in PubMed, Web of Science, and PsycInfo databases up to January 2025. Studies were eligible if they included adult cancer survivors, measured psychological distress using validated instruments at minimum two time points, and employed longitudinal cohort designs. Quality assessment used a modified Newcastle-Ottawa Scale. A narrative synthesis was performed due to study heterogeneity.

resultsOf 5028 records screened, 41 studies met criteria, representing diverse geographical regions and cancer types (sample sizes: 74-6054 participants). Eleven examined distress-survival associations; 30 focused on longitudinal changes. Studies identified 2-6 distinct trajectory patterns, with most survivors maintaining low distress levels while a minority experienced chronically elevated symptoms. Persistent or worsening psychological distress was consistently associated with worse survival outcomes across cancer types, while survivors recovering from initial symptoms showed survival rates comparable to those never experiencing distress.

conclusionsLongitudinal psychological distress patterns may carry prognostic value in cancer survivors, with persistent or worsening symptoms generally associated with worse survival outcomes, though effect sizes varied and findings were not uniformly consistent. These findings suggest a potential role for longitudinal distress monitoring during survivorship care. Whether modifying distress trajectories through psychosocial interventions can improve survival remains unclear and warrants further investigation.

Indexed as

Cancer SurvivorsNeoplasmsPsychological DistressStress, PsychologicalHumansPrognosisSurvival Rateanxietycancer survivorsdepressionlongitudinal studiespsychological distresssurvivalsurvivorship

Identifiers

PMID42138343
PMCPMC13178206

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.