Evidence map›Paper›PMID 42138310›Full record

ArticleJournal of immunology research2026

Induction of HIV-Specific T Cell Responses Using αDC1 Pulsed With Conserved HIV-1 Peptides.

Laís Teodoro Da Silva, Marina Mazzilli Ortega, Silvia de Jesus Mota, Guilherme Castellani, Dennyson Leandro M Fonseca, Larissa Danielle Bahls Pinto, Gabriela Justamante Handel Schmitz, Isabela Leite, Theo Leite, Mariana Amelia Monteiro and 4 more

Abstract read
In one paragraph

Article in Journal of immunology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Laís Teodoro Da SilvaLaboratory of Medical Investigation in Dermatology and Immunodeficiencies (LIM-56), Hospital das Clinicas HCFMUSP, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0001-8542-802X
Marina Mazzilli OrtegaLaboratory of Medical Investigation in Dermatology and Immunodeficiencies (LIM-56), Hospital das Clinicas HCFMUSP, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0003-3258-8315
Silvia de Jesus MotaLaboratory of Medical Investigation in Dermatology and Immunodeficiencies (LIM-56), Hospital das Clinicas HCFMUSP, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0009-0003-9789-7861
Guilherme CastellaniLaboratory of Medical Investigation in Dermatology and Immunodeficiencies (LIM-56), Hospital das Clinicas HCFMUSP, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0002-5474-254X
Dennyson Leandro M FonsecaLaboratory of Molecular Immunology Research miRlab, School of Arts, Science and Humanities (EACH), University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0003-2567-5808
Larissa Danielle Bahls PintoDepartment of Clinical Analysis and Biomedicine (DAB), Postgraduate Program in Biosciences and Physiopathology (PBF), Maringá, Brazil.ORCID https://orcid.org/0000-0001-6469-3123
Gabriela Justamante Handel SchmitzLaboratory of Medical Investigation in Dermatology and Immunodeficiencies (LIM-56), Hospital das Clinicas HCFMUSP, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0002-7069-1017
Isabela LeiteLaboratory of Medical Investigation in Dermatology and Immunodeficiencies (LIM-56), Hospital das Clinicas HCFMUSP, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0009-0007-3099-2986
Theo LeiteLaboratory of Medical Investigation in Dermatology and Immunodeficiencies (LIM-56), Hospital das Clinicas HCFMUSP, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0009-0009-7863-2896
Mariana Amelia MonteiroLaboratory of Medical Investigation in Dermatology and Immunodeficiencies (LIM-56), Hospital das Clinicas HCFMUSP, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0002-6015-9924
Sandra Marcia MuxelLaboratory of Molecular Immunology Research miRlab, School of Arts, Science and Humanities (EACH), University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0003-0118-5361
Robbie B MailliardDepartment of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, 15261, Pennsylvania, USA, pitt.edu.ORCID https://orcid.org/0000-0001-5501-503X
Alberto José da Silva DuarteLaboratory of Medical Investigation in Dermatology and Immunodeficiencies (LIM-56), Hospital das Clinicas HCFMUSP, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0002-8707-4904
Telma Miyuki OshiroLaboratory of Medical Investigation in Dermatology and Immunodeficiencies (LIM-56), Hospital das Clinicas HCFMUSP, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0002-8791-9233

Funding

WG3: HIV, Co-infections and Co-morbiditiesP30AI036219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI Alan David Levine · 1994 to 2026
$50.0M
Antigen-specific ‘kick and kill’ of the latent HIV reservoir using dendritic cellsR01AI152655 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Robbie B Mailliard · 2022 to 2026
$3.2M
Case/UHC-Pitt Center for AIDS Research (Rustbelt CFAR) 2P30AI036219-26A1Conselho Nacional de Desenvolvimento Científico e Tecnológico 303384/2024-7Conselho Nacional de Desenvolvimento Científico e Tecnológico 304043/2022-2Conselho Nacional de Desenvolvimento Científico e Tecnológico 305135/20198Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 138377/2025-1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.196649/2025-00Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.251198/2026-00Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.970045/2024-00CSD-UEM 1589/2017Fundação de Amparo à Pesquisa do Estado de São Paulo 16/25212-9Fundação de Amparo à Pesquisa do Estado de São Paulo 21/06139-7Fundação de Amparo à Pesquisa do Estado de São Paulo 23/11990-3Fundação de Amparo à Pesquisa do Estado de São Paulo 23/14374-1Fundação de Amparo à Pesquisa do Estado de São Paulo 24/08360-0Fundação de Amparo à Pesquisa do Estado de São Paulo 24/08802-3Fundação de Amparo à Pesquisa do Estado de São Paulo 24/14088-1Fundação de Amparo à Pesquisa do Estado de São Paulo 25/03433-2Fundação de Amparo à Pesquisa do Estado de São Paulo 25/12297-5Fundação de Amparo à Pesquisa do Estado de São Paulo 25/13425-7NIAID NIH HHS P30 AI036219NIAID NIH HHS R01 AI152655
6 · The paper itself

Abstract

Despite the effectiveness of antiretroviral therapy (ART) in suppressing HIV-1 replication and reducing morbidity, viral eradication remains unachievable due to the persistence of latent reservoirs, particularly within memory CD4

Indexed as

Dendritic CellsHIV-1HIV InfectionsCell DifferentiationCells, CulturedCoculture TechniquesCytokinesHIV AntigensHumansInterleukin-12Lymphocyte ActivationPeptidesCytokinesHIV AntigensInterleukin-12Peptides

Identifiers

PMID42138310
PMCPMC13177841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.