Evidence map›Paper›PMID 42137910›Full record

ArticleNature. Mental health2026

Optimizing functional connectivity scanning conditions for predicting autistic traits.

Corey Horien, Francesca Mandino, Abigail S Greene, Xilin Shen, Kelly Powell, Angelina Vernetti, David O'Connor, Brendan D Adkinson, Link Tejavibulya, James C McPartland and 9 more

Abstract read
In one paragraph

Article in Nature. Mental health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Corey HorienDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA USA.ORCID 0000-0001-6738-1029
Francesca MandinoDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT USA.ORCID 0000-0002-5605-0854
Abigail S GreeneMD-PhD Program, Yale School of Medicine, New Haven, CT USA.
Xilin ShenDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT USA.
Kelly PowellChild Study Center, Yale School of Medicine, New Haven, CT USA.
Angelina VernettiChild Study Center, Yale School of Medicine, New Haven, CT USA.
David O'ConnorBioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY USA.ORCID 0000-0002-8885-518X
Brendan D AdkinsonMD-PhD Program, Yale School of Medicine, New Haven, CT USA.
Link TejavibulyaDepartment of Radiology, Weill Cornell Medicine, New York, NY USA.
James C McPartlandChild Study Center, Yale School of Medicine, New Haven, CT USA.ORCID 0000-0002-2570-0746
Fred R VolkmarChild Study Center, Yale School of Medicine, New Haven, CT USA.
Marvin ChunDepartment of Psychology, Yale University, New Haven, CT USA.
Katarzyna ChawarskaChild Study Center, Yale School of Medicine, New Haven, CT USA.ORCID 0000-0002-1445-6346
Evelyn M R LakeDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT USA.
Monica D RosenbergDepartment of Psychology, University of Chicago, Chicago, IL USA.ORCID 0000-0001-6179-4025
Theodore SatterthwaiteDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA USA.ORCID 0000-0001-7072-9399
Dustin ScheinostDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT USA.ORCID 0000-0002-6301-1167
Emily S FinnDepartment of Psychological and Brain Sciences, Dartmouth College, Dartmouth, NH USA.ORCID 0000-0001-8591-3068
R Todd ConstableMD-PhD Program, Yale School of Medicine, New Haven, CT USA.ORCID 0000-0001-5661-9521

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism is a heterogeneous condition, and functional magnetic resonance imaging-based studies have advanced understanding of neurobiological correlates of autistic features. Little work has focused on the optimal brain states to reveal brain-phenotype relationships. Here, using connectome-based predictive modeling, we interrogated four datasets to determine scanning conditions that boost prediction of clinically relevant phenotypes and assess generalizability. In dataset one, a sample of youth with autism and neurotypical participants (

Indexed as

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Identifiers

PMID42137910
PMCPMC13167459

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.