ArticleEJHaem2026
Plasma Levels of Retinoids and Carotenoids in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation Given Extracorporeal Photopheresis to Prevent Graft-Versus-Host Disease-Analyses From a Randomized Trial.
Article in EJHaem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03204721 (Prevention of Graft-versus-host Disease in Patients Treated With Allogeneic Stem Cell Transplantation), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevention of Graft-versus-host Disease in Patients Treated With Allogeneic Stem Cell Transplantation: Possible Role of Extracorporeal Photophoresis
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Whether retinoids and carotenoids impact on graft-versus-host disease (GVHD) following allogeneic stem cell transplantation (ASCT) is unknown. Methods: We conducted a 1:1 randomized controlled trial with extracorporeal photopheresis for GVHD-prophylaxis as the intervention. The plasma levels of retinoids and carotenoids were determined at randomization and 3 months after ASCT. Results: We found no significant difference in GVHD occurrence and levels of retinoids between the intervention and control groups at either of the two time points. Conclusion: Whether routine vitamin A supplementation is warranted for GVHD prevention, needs further study. Our exploratory study highlights the complex role of retinoid homeostasis in immune function during ASCT. Trial Registration: ClinicalTrials.gov identifier: NCT03204721.
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