ArticleInfection and drug resistance2026
Artificial Sweeteners Induce Bacterial Drug Resistance and Modulate Gene Expression.
Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
11 authors.
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Abstract
Objective: To explore the effects of artificial sweeteners on reduced antibiotic susceptibility and expression of antibiotic resistance and virulence-related genes in bacteria exposed to permitted daily intake levels. Methods: We first evaluated the antibacterial effects of five commonly used artificial sweeteners (saccharin, cyclamate, aspartame, acesulfame potassium, and sucralose) on Results: The minimum inhibitory concentration (MIC) of artificial sweeteners for Conclusions: Exposure to artificial sweeteners at CAC-permitted doses is associated with reduced antibiotic susceptibility and may affect bacterial function. Therefore, the safety of artificial sweeteners as substitutes for natural sugars requires careful consideration and further in vivo validation.
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