Evidence map›Paper›PMID 42137681›Full record

ArticleCureus2026

Sinus Arrest Associated With a COVID-19 Nasopharyngeal Swab Procedure: A Case Report.

Robert M Lester, Sabina Paglialunga

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Robert M LesterCardiac Safety Services, Celerion, Tempe, USA.
Sabina PaglialungaScientific Affairs, Celerion, Tempe, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the COVID-19 pandemic, nasal swabs became a routine test for infection. This non-invasive procedure is typically regarded as benign and rarely associated with complications. However, physical stimulation of the nasopharynx and trigeminal nerve can trigger the trigeminocardiac reflex (TCR), a vagally mediated cardioinhibitory response that can lead to sinus arrest. In this study, a clinical trial participant experienced a 3.4 s episode of sinus arrest which was captured on electrocardiogram telemetry during a routine COVID-19 nasal swab test. Diagnosis of the TCR was based upon the plausibility and reversibility criteria, which are hallmarks of this condition. Healthcare providers need to be aware of this phenomenon as well as other potential complications when performing nasopharyngeal swabs.

Indexed as

covid-19electrocardiogram (ecg)holter monitoringnasopharyngeal swabtrigeminocardiac reflex

Identifiers

PMID42137681
PMCPMC13171233

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.