Evidence map›Paper›PMID 42137651›Full record

ArticleCureus2026

Rapidly Progressive Giant Malignant Phyllodes Tumor of the Breast: A Surgical Challenge.

Georgia Xanthopoulou, Kyriaki Theodorolea, Christos Barkolias, Ilektra Spyrou, Nikolaos P Tasis

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Georgia XanthopoulouDepartment of Surgery, Naval and Veterans Hospital of Athens, Athens, GRC.
Kyriaki TheodoroleaDepartment of Surgery, Naval and Veterans Hospital of Athens, Athens, GRC.
Christos BarkoliasDepartment of Surgery, Naval and Veterans Hospital of Athens, Athens, GRC.
Ilektra SpyrouDepartment of Surgery, Naval and Veterans Hospital of Athens, Athens, GRC.
Nikolaos P TasisDepartment of Surgery, Naval and Veterans Hospital of Athens, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant phyllodes tumors are rare fibroepithelial breast neoplasms that may pose significant diagnostic and surgical challenges, particularly when they reach extreme dimensions. Complete surgical excision with adequate margins remains the cornerstone of treatment. We report the case of a 65-year-old female who presented with a progressively enlarging mass of the left breast over an 18-month period. Clinical examination revealed a massive palpable lesion occupying nearly the entire breast, resulting in marked distortion of the breast architecture. Due to the extensive size of the tumor, conventional imaging modalities could not be adequately performed. Core needle biopsy demonstrated findings consistent with a malignant phyllodes tumor. The patient subsequently underwent left mastectomy, and histopathological examination confirmed complete excision of a 29 × 26 × 17 cm mass with negative, adequate margins. Eight months postoperatively, a local recurrence was identified along the mastectomy scar. The patient underwent wide local excision of the recurrent lesion followed by flap reconstruction. At three-year follow-up, the patient remains free of disease recurrence.

Indexed as

breast cystosarcomagiant phyllodes tumourmalignant phyllodes recurrencemalignant phyllodes tumourphyllodesphyllodes tumour

Identifiers

PMID42137651
PMCPMC13169467

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.