ArticleFrontiers in psychiatry2026
The significance of personality disorder and traits in short-term psychodynamic and cognitive behavioral therapy for major depression.
Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Research has shown inconsistent results regarding the impact of personality disorder (PD) on psychotherapy outcomes for depression. There is a scarcity of studies comparing cognitive behavioral therapy (CBT) with short-term psychodynamic therapy (STPP). This study aimed to compare outcome of STPP and CBT in depressed patients with and without PD and investigate whether PD or specific PD traits differentially affected outcome in STPP and CBT. Methods: One hundred outpatients with major depression (PD, n=28; NoPD, n=72) were randomized to STPP or CBT and followed up after 28 weeks. PD was assessed by semi-structured interview (SCID-II) which indicated mild to moderate severity of PD. Primary outcome measures were Hamilton Depression Rating Scale and Beck Depression Inventory-II, secondary outcome measures were the Global Functioning Scale, Work and Social Adjustment Scale and Generalized Anxiety Disorder 7. Statistics comprised bivariate analyses and multivariate linear regression. Results: Effect sizes for primary and secondary outcomes were large for both the PD and NoPD groups, with no significant difference in clinical status between the groups after 28 weeks. The presence of a PD diagnosis did not moderate outcome of STPP versus CBT, but the interaction between paranoid traits and treatment showed a significant effect in favor of STPP. Conclusions: The results indicate that co-occurring mild to moderate personality pathology should not be a barrier to standard psychotherapies for patients with depression. More studies are needed to investigate whether type and complexity of personality pathology differentially affect short- and longer-term outcomes of different psychotherapies for depressed patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.