ArticleFrontiers in surgery2026
Bilateral approach selection in neuroendoscopic surgery for pituitary adenomas and health economic evaluation.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the impact of bilateral approach selection in neuroendoscopic transsphenoidal surgery for pituitary adenomas on patient prognosis and to analyze the medical burden on patients from a health economic perspective. Methods: A retrospective analysis was conducted on the data of 197 patients who underwent pituitary adenoma surgery. The patients were divided into two groups based on the surgical approach: the transseptal approach group ( Results: Compared with the bilateral nostril expanded transsphenoidal approach, the transseptal approach was associated with significantly less intraoperative blood loss and shorter operative time ( Conclusion: The transseptal approach in pituitary adenoma surgery has the advantages of less intraoperative bleeding and shorter surgical duration, which can reduce postoperative anxiety and depression in patients. Postoperative nasal packing may reduce complications, but larger multicenter studies are warranted. Pituitary adenoma patients bear substantial economic and psychological burdens; multidisciplinary collaboration and pharmacoeconomic optimization are needed to reduce overall costs and improve outcomes.
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