Evidence map›Paper›PMID 42137318›Full record

ReviewFrontiers in pharmacology2026

Point-of-care testing reduces antibiotic prescribing for adults with community-acquired pneumonia: a systematic review and meta-analysis.

Wenshuai Ji, Kai Xie, Kang Zhang, Yingjin Liang, Yikun Wang, Hao Yang, Yifan Han, Wenjing Yin, Haifeng Wang

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenshuai Ji *Department of Respiratory Medicine, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Kai XieDepartment of Respiratory Medicine, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Kang ZhangDepartment of Respiratory Medicine, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Yingjin LiangDepartment of Respiratory Medicine, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Yikun WangAcademy of Chinese Medical Sciences, The First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou, China.
Hao YangDepartment of Respiratory Medicine, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Yifan HanDepartment of Respiratory Medicine, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Wenjing YinDepartment of Respiratory Medicine, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Haifeng WangDepartment of Respiratory Medicine, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate the impact of point-of-care testing (POCT) on antibiotic prescribing and clinical outcomes in adult patients with community-acquired pneumonia (CAP) through a systematic review and meta-analysis. Methods: Web of Science, Scopus, Embase, PubMed, and Cochrane Library were searched for randomized controlled trials (RCTs). The final search was conducted on June 2025. Outcomes included both antibiotic-related and clinical outcomes. The meta-analysis was performed using Review Manager. The study was registered with PROSPERO (CRD420251035572). Results: Nine RCTs involving 2,899 participants were included. POCT significantly reduced the proportion of adult CAP patients receiving antibiotic prescriptions by 10% (RD = -0.10; 95% CI: -0.15 to -0.05, Conclusion: POCT may reduce antibiotic exposure in patients with CAP without compromising clinical outcomes. As diagnostic innovation plays an increasingly important role in combating antimicrobial resistance, POCT should be used selectively as an adjunct to clinical judgment.

Indexed as

antibioticscommunity-acquired pneumoniameta-analysispoint-of-care testingprocalcitonin

Identifiers

PMID42137318
PMCPMC13167562

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.