ArticleFrontiers in physiology2026
Analysis of fatty acids concentration in the liver of rats with diet-induced obesity after bariatric surgery and a high-fat/high-sugar diet.
Article in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Obesity is a leading risk factor for metabolic diseases, but the effects of bariatric surgery on hepatic fatty acid profiles remain poorly understood. This study investigated how duodenojejunal omega switch (DJOS) bariatric surgery and dietary patterns alter fatty acid composition in the liver of rats with diet-induced obesity. Methods: Fifty-six male Sprague-Dawley rats were fed either a control or a high-fat/high-sugar diet, then assigned to DJOS or SHAM surgery, followed by maintenance or a switch in dietary regimen for eight weeks postoperatively. Liver fatty acids were quantified using gas chromatography-mass spectrometry. Results and discussion: DJOS surgery combined with a high-fat/high-sugar diet led to significantly higher concentrations of select long- and very-long-chain fatty acids (C14:0, C15:0, C22:0, C24:1, C24:0) versus SHAM, while dietary change post-surgery (CD/CF) reduced concentrations of C17:0, C18:0, C20:4n6, C20:5n3, C22:n6-3, and C24:0 in SHAM-operated rats. Additionally, lower levels of a total mixture of C18:1n9c, C18:2n6t, and C18:3n3 were observed when diet quality improved after SHAM surgery. The findings highlight complex interactions between surgical intervention and dietary composition in modulating hepatic fatty acid metabolism, emphasizing the importance of both approaches in obesity-related metabolic management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.