Evidence map›Paper›PMID 42137026›Full record

ArticlePlant biotechnology (Tokyo, Japan)2026

Production of recombinant human transferrin using transgenic rice cell culture.

Arisa Kubomura, Yuki Katayama, Yasuko Matsukura, Hayuma Otsuka, Toshiyuki Saeki, Kanako Sasaki, Ei-Tora Yamamura, Hiroyuki Kajiura, Jong-Kook Lee, Kazuhito Fujiyama and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant biotechnology (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Arisa KubomuraKirin Central Research Institute, Research & Development Division, Kirin Holdings Company, Ltd., 2-26-1 Muraoka-Higashi, Fujisawa, Kanagawa 251-8555, Japan.
Yuki KatayamaKirin Central Research Institute, Research & Development Division, Kirin Holdings Company, Ltd., 2-26-1 Muraoka-Higashi, Fujisawa, Kanagawa 251-8555, Japan.
Yasuko MatsukuraKirin Central Research Institute, Research & Development Division, Kirin Holdings Company, Ltd., 2-26-1 Muraoka-Higashi, Fujisawa, Kanagawa 251-8555, Japan.
Hayuma OtsukaKirin Central Research Institute, Research & Development Division, Kirin Holdings Company, Ltd., 2-26-1 Muraoka-Higashi, Fujisawa, Kanagawa 251-8555, Japan.
Toshiyuki SaekiKirin Central Research Institute, Research & Development Division, Kirin Holdings Company, Ltd., 2-26-1 Muraoka-Higashi, Fujisawa, Kanagawa 251-8555, Japan.
Kanako SasakiKirin Central Research Institute, Research & Development Division, Kirin Holdings Company, Ltd., 2-26-1 Muraoka-Higashi, Fujisawa, Kanagawa 251-8555, Japan.
Ei-Tora YamamuraKirin Central Research Institute, Research & Development Division, Kirin Holdings Company, Ltd., 2-26-1 Muraoka-Higashi, Fujisawa, Kanagawa 251-8555, Japan.
Hiroyuki KajiuraInternational Center for Biotechnology, The University of Osaka, 2-1 Yamada-oka, Suita, Osaka 565-0871, Japan.
Jong-Kook LeeDepartment of Cardiovascular Regenerative Medicine and Drug Discovery, The University of Osaka Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan.
Kazuhito FujiyamaInternational Center for Biotechnology, The University of Osaka, 2-1 Yamada-oka, Suita, Osaka 565-0871, Japan.
Hiroshi OkawaKirin Central Research Institute, Research & Development Division, Kirin Holdings Company, Ltd., 2-26-1 Muraoka-Higashi, Fujisawa, Kanagawa 251-8555, Japan.
Kazuaki OharaKirin Central Research Institute, Research & Development Division, Kirin Holdings Company, Ltd., 2-26-1 Muraoka-Higashi, Fujisawa, Kanagawa 251-8555, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transferrin is one of the major soluble serum proteins and is responsible for iron transport. Industrially, it is significant as a component of mammalian cell culture media, where a safe and stable supply is necessary. However, because transferrin is a glycoprotein containing 19 disulfide bonds, it is difficult to produce as a recombinant protein in bacteria, and at present it is mainly sourced from animals. In glycoprotein production, stability of the

Indexed as

N-glycan profilerecombinant proteinricetransferrin

Identifiers

PMID42137026
PMCPMC13170787

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.