Evidence map›Paper›PMID 42136915›Full record

ReviewJRSM cardiovascular disease

Coronary atherectomy versus balloon angioplasty before drug-eluting stent implantation in severely calcified lesions: A systematic review and meta-analysis.

Omar Kasimieh, Yashaswi Guntupalli, Prapti Atul Patel, Lydia Susan Abraham, Thomas Viji Pulickal, Md Arif Hasan Bhuiyan, Milikyas Abera Feyisa, Mohammed Bushnaq, Rohit Mote Reddy, Shiva Mokhtassi and 5 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in JRSM cardiovascular disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Omar KasimiehDepartment of Medicine, University of the East Ramon Magsaysay Memorial Medical Center, Quezon City, Philippines.
Yashaswi GuntupalliDepartment of Internal Medicine, Sri Venkateswara Institute of Medical Sciences, Andhra Pradesh, Tirupati, India.
Prapti Atul PatelDepartment of Medicine, GMERS Medical College and Hospital, Himmatnagar, India.
Lydia Susan AbrahamAneurin Bevan Health Board, Newport, UK.
Thomas Viji PulickalDepartment of Medicine, All India Institute of Medical Sciences, Bhubaneswar, India.
Md Arif Hasan BhuiyanDepartment of Cardiology, Croydon University Hospital, London, UK.
Milikyas Abera FeyisaGeneral Internal Medicine Department, Naas General Hospital, Kildare, Ireland.
Mohammed BushnaqDepartment of Medicine, Jordan University Hospital, Amman, Jordan.
Rohit Mote ReddyDepartment of Medicine, Bhaskar Medical College, Hyderabad, India.ORCID https://orcid.org/0009-0000-4967-6544
Shiva MokhtassiDepartment of Cardiothoracic Surgery, St George's Hospital, London, UK.
Arooba EjazDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Asma'a Munasar Ali AlsubariFaculty of Medicine, Sana'a University, Sana'a, Yemen.ORCID https://orcid.org/0009-0004-8092-7072
Vaibhav VatsDepartment of Internal Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, New York, NY, USA.
Talal AlmasUniversity Hospitals Cleveland medical Centre, Case Western Reserve University, Cleveland, OH, USA.
Huzaifa Ahmad CheemaDepartment of Cardiology, King Edward Medical University, Lahore, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe coronary calcification can impede stent delivery and affect long-term outcomes. Few trials have compared coronary atherectomy with balloon-first strategies for lesion preparation before drug-eluting stent (DES) implantation. Methods: We searched MEDLINE, Embase, and the Cochrane Library through October 2025 for randomized controlled trials (RCTs) comparing coronary atherectomy with balloon angioplasty for lesion preparation before DES implantation in severely calcified coronary lesions. Results: Across three RCTs, there was no significant difference in major adverse cardiovascular events between atherectomy and balloon angioplasty (risk ratio [RR] 1.05, 95% confidence interval [CI] 0.85-1.30; Conclusions: Our meta-analysis showed that routine atherectomy was comparable with balloon angioplasty in severely calcified coronary lesions. These findings support a selective, imaging-guided balloon-first strategy, reserving atherectomy for lesions that remain undilatable or uncrossable. Randomized studies of imaging-guided algorithms and emerging technologies are needed to define optimal lesion-specific strategies.

Indexed as

Atherectomyballoon angioplastycalcified coronary lesionsdrug-eluting stent

Identifiers

PMID42136915
PMCPMC13167278

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.