Evidence map›Paper›PMID 42136834›Full record

ArticleFrontiers in medicine2026

Resident T cell activation leads to human hair follicle immune privilege loss

Ilaria Piccini, Thomas Rouillé, Wolfgang Funk, Francisco Jimenez, Alexandre Kaoukhov, Carl Firth, Amos Gilhar, Janin Edelkamp, Ferda Cevikbas, Marta Bertolini

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ilaria Piccini *QIMA Life Sciences, QIMA Monasterium GmbH, Münster, Germany.
Thomas Rouillé *QIMA Life Sciences, QIMA Monasterium GmbH, Münster, Germany.
Wolfgang FunkClinic for Plastic, Aesthetic and Reconstructive Surgery Dr. Dr. med. Funk, Munich, Germany.
Francisco JimenezMediteknia Clinic, Las Palmas de Gran Canaria, Spain.
Alexandre KaoukhovASLAN Pharmaceuticals, San Mateo, CA, United States.
Carl FirthASLAN Pharmaceuticals, San Mateo, CA, United States.
Amos GilharTechnion-Israel Institute of Technology, Haifa, Israel.
Janin EdelkampQIMA Life Sciences, QIMA Monasterium GmbH, Münster, Germany.
Ferda CevikbasASLAN Pharmaceuticals, San Mateo, CA, United States.
Marta BertoliniQIMA Life Sciences, QIMA Monasterium GmbH, Münster, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The autoimmune hair loss disorder alopecia areata (AA), is characterized by immune privilege (IP) collapse of the hair follicle (HF) bulb resulting from a Th1-dependent inflammatory response. Although CD8

Indexed as

alopecia areataDHODH inhibitionfarudodstathair follicle organ cultureimmune privilegeT cell proliferationT cell receptor

Identifiers

PMID42136834
PMCPMC13169153

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.