ArticlePakistan journal of medical sciences2026
Laparoscopic nephrectomy for Xanthogranulomatous Pyelonephritis: First surgical outcomes report from Pakistan.
Article in Pakistan journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: The aim of this study was to analyze the perioperative and postoperative outcomes of laparoscopic nephrectomy (LN) in the management of patients with xanthogranulomatous pyelonephritis (XGPN). Methodology: This retrospective review examined medical records of patients who underwent LN for histopathologically confirmed XGPN at the Aga Khan University Hospital, Pakistan, from January 2019 to October 2024. Patient demographics, clinical presentation, microbiological findings, imaging results, operative details, and postoperative outcomes including hospital stay, complications, and 30-day readmission were evaluated. Results: A total of 13 LNs were performed for XGPN. The mean patient age was 49.6 ± 17.3 years, with females accounting for 61.5% of cases. Flank pain was the most common presenting symptom, while hypertension and diabetes mellitus were the most frequent comorbidities (23.1% each). Most preoperative urine cultures were negative; among positive cultures, Conclusion: Laparoscopic nephrectomy is a feasible, safe, and effective treatment option for XGPN in our setting and is associated with favorable surgical outcomes.
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