Evidence map›Paper›PMID 42136744›Full record

ArticleFrontiers in cellular and infection microbiology2026

Hongdong Zhao, Chi Zhu, Shengxin Ye, Zhimin Bai, Zhiqiang Liu, Xin Dong, Yirong Zhang, Huizhen Chen, Jinjing Wu, Yinfeng Su and 2 more

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hongdong Zhao *Department of Clinical Laboratory, Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian), Jinjiang, Fujian, China.
Chi Zhu *Department of Clinical Laboratory, Hangzhou Adicon Medical Laboratory Co., Ltd., Hangzhou, China.
Shengxin Ye *Department of Clinical Laboratory, Hangzhou Adicon Medical Laboratory Co., Ltd., Hangzhou, China.
Zhimin BaiDepartment of Clinical Laboratory, Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian), Jinjiang, Fujian, China.
Zhiqiang LiuDepartment of Clinical Laboratory, Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian), Jinjiang, Fujian, China.
Xin DongDepartment of Clinical Laboratory, Hangzhou Adicon Medical Laboratory Co., Ltd., Hangzhou, China.
Yirong ZhangDepartment of Clinical Laboratory, Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian), Jinjiang, Fujian, China.
Huizhen ChenDepartment of Clinical Laboratory, Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian), Jinjiang, Fujian, China.
Jinjing WuDepartment of Clinical Laboratory, Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian), Jinjiang, Fujian, China.
Yinfeng SuDepartment of Clinical Laboratory, Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian), Jinjiang, Fujian, China.
Yang WangDepartment of Clinical Laboratory, Hangzhou Adicon Medical Laboratory Co., Ltd., Hangzhou, China.
Kaizhen WenDepartment of Clinical Laboratory, Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian), Jinjiang, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: We integrated clinical data, antimicrobial susceptibility testing, and whole-genome sequencing (WGS) for four Results: A 53-year-old uncontrolled type 2 diabetes patient developed septic shock with pronounced inflammatory response (PCT 13.32 ng/mL, CRP 364.85 mg/L). WGS confirmed 0 core-genome SNP differences between blood (20250131) and wound (20250137) isolates, validating clonal transmission from the foot ulcer. All four institutional isolates were ST2250, sharing 12 core antimicrobial resistance-associated (AMR) genes. Global analysis identified the dominance of ST2250 (55.9% of 370 genomes), with 101 out of 147 (68.7%) observed between 2015 and 2019 among the dated genomes (68.7% of 268 genomes with a known collection year). ST2250 exhibited unique AMR signatures: highest Conclusions: This study provides genetic validation of

Indexed as

Diabetic FootDrug Resistance, BacterialSepsisStaphylococcal InfectionsStaphylococcusAnti-Bacterial AgentsDiabetes Mellitus, Type 2Genome, BacterialGenomicsHumansMaleMicrobial Sensitivity TestsMiddle AgedPolymorphism, Single NucleotideVirulenceVirulence FactorsAnti-Bacterial AgentsVirulence Factorsantimicrobial resistancediabetic foot infectionsepsisST2250Staphylococcus argenteusvirulence geneswhole-genome sequencing

Identifiers

PMID42136744
PMCPMC13167990

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.