Evidence map›Paper›PMID 42136737›Full record

ArticleFrontiers in cellular and infection microbiology2026

Robot-assisted gait training alleviates the symptoms of acute ischemic stroke via regulating gut microbiota composition and function.

Haijie Liu, Bo Han, Hui Yao, Junjie Wang, Fang Xv, Yujie Xv, Meng Zhang, Ming Lin, Zeguang Li, Sen Wang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Haijie Liu *Department of Neurology, Xuanwu Hospital Capital Medical University, National Center for Neuro-logical Disorders, Beijing, China.
Bo Han *Department of Neurology, Xuanwu Hospital Capital Medical University, National Center for Neuro-logical Disorders, Beijing, China.
Hui Yao *Department of Neurology, Xuanwu Hospital Capital Medical University, National Center for Neuro-logical Disorders, Beijing, China.
Junjie WangDepartment of Neurology, Xuanwu Hospital Capital Medical University, National Center for Neuro-logical Disorders, Beijing, China.
Fang XvDepartment of Neurology, Xuanwu Hospital Capital Medical University, National Center for Neuro-logical Disorders, Beijing, China.
Yujie XvDepartment of Neurology, Xuanwu Hospital Capital Medical University, National Center for Neuro-logical Disorders, Beijing, China.
Meng ZhangDepartment of Neurology, Xuanwu Hospital Capital Medical University, National Center for Neuro-logical Disorders, Beijing, China.
Ming LinDepartment of Neurology, Xuanwu Hospital Capital Medical University, National Center for Neuro-logical Disorders, Beijing, China.
Zeguang LiDepartment of Neurology, Baoding No. 1 Central Hospital, Baoding, Hebei, China.
Sen WangDepartment of Neurology, Baoding No. 1 Central Hospital, Baoding, Hebei, China.
Yuting ZhangDepartment of Neurology, Baoding No. 1 Central Hospital, Baoding, Hebei, China.
Juan GaoDepartment of Neurology, Baoding No. 1 Central Hospital, Baoding, Hebei, China.
Yanming ZhangDepartment of Rehabilitation Medicine, Xuanwu Hospital Capital Medical University, National Center for Neuro-logical Disorders, Beijing, China.
Peng ZhangTianjin Key Laboratory of Life and Health Detection, Life and Health Intelligent Research Institute, Tianjin University of Technology, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Robot-assisted gait training (RAGT) improves motor recovery after stroke, yet its biological mechanisms remain poorly understood. Increasing evidence suggests that gut microbiota dysbiosis contributes to stroke pathology and recovery. Methods: Forty-seven newly diagnosed AIS patients were enrolled and assigned to a RAGT group (IG, Results: Compared with CG patients, IG patients demonstrated significantly improved clinical outcomes. RAGT partially reversed stroke-associated gut dysbiosis, characterized by increased microbial richness and evenness. Beneficial taxa, including Conclusion: Poststroke RAGT was associated with alteration of gut microbiota composition and function, suggesting a novel microbiota-mediated mechanism underlying its neurorehabilitative benefits in AIS.

Indexed as

DysbiosisGaitGait Disorders, NeurologicGastrointestinal MicrobiomeIschemic StrokeRoboticsAgedFecesFemaleHumansMaleMiddle AgedRNA, RibosomalStroke RehabilitationTreatment OutcomeRNA, RibosomalRNA, ribosomal, 26S16S rRNA sequencingacute ischemic strokedysbiosisgut microbiotarobot-assisted gait training

Identifiers

PMID42136737
PMCPMC13168169

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.