Evidence map›Paper›PMID 42136733›Full record

ArticleJBMR plus2026

Effects of comorbid chronic kidney disease on late-onset hypophosphatasia mice under treatment with asfotase alfa.

Cintia Tokuhara, Flavia Amadeu de Oliveira, Sonoko Narisawa, Elis J Lira Dos Santos, Brian L Foster, Jose Luis Millan

Abstract read
In one paragraph

Article in JBMR plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cintia TokuharaSanford Children's Health Research Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, United States.ORCID https://orcid.org/0000-0002-1852-5986
Flavia Amadeu de OliveiraSanford Children's Health Research Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, United States.ORCID https://orcid.org/0000-0003-3063-6694
Sonoko NarisawaSanford Children's Health Research Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, United States.ORCID https://orcid.org/0000-0002-2118-6380
Elis J Lira Dos SantosDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH 43210, United States.ORCID https://orcid.org/0000-0002-0324-3863
Brian L FosterDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH 43210, United States.ORCID https://orcid.org/0000-0003-3444-0576
Jose Luis MillanSanford Children's Health Research Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, United States.ORCID https://orcid.org/0000-0002-1547-2671

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypophosphatasia (HPP) is a rare bone disorder caused by loss-of-function mutations in the

Indexed as

CKD-mineral and bone disorderhypophosphatasialoss-of-functionmousepreclinical model

Identifiers

PMID42136733
PMCPMC13171041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.