Evidence map›Paper›PMID 42136657›Full record

ArticleFrontiers in immunology2026

Clinical, laboratory and genetic characteristics of VEXAS syndrome: a study on behalf of GESMD.

Marta Fonseca-Santos, Borja Puertas, Javier Arzuaga-Méndez, Idoya Ancin-Arteaga, Sandra Castaño-Diez, Carlos De Miguel, Marta Canet-Maldonado, Marc Bosch-Schips, Pablo Palomo-Rumschisky, María Laura Blanco and 18 more

Abstract readMulticenter Study
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Marta Fonseca-Santos *Servicio de Hematología, Hospital Universitario de Salamanca (HUS), Salamanca, Spain.
Borja Puertas *Servicio de Hematología, Hospital Universitario de Salamanca (HUS), Salamanca, Spain.
Javier Arzuaga-MéndezGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Idoya Ancin-ArteagaGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Sandra Castaño-DiezGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Carlos De MiguelGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Marta Canet-MaldonadoGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Marc Bosch-SchipsGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Pablo Palomo-RumschiskyGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
María Laura BlancoGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Daniel Gil-AlósGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
María Moreno-IgoaGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Pedro G Santa-CatalinaOncology Department, Hospital Universitario de Salamanca, IBSAL, Salamanca, Spain.
Raúl AzibeiroServicio de Hematología, Hospital Universitario de Salamanca (HUS), Salamanca, Spain.
Carlos PuertaServicio de Hematología, Hospital Universitario de Salamanca (HUS), Salamanca, Spain.
Alba Mesa-TudelaGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Felix López-CadenasGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Esperanza TusetGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Dolly Viviana Fiallo-SuarezGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Fernando RamosGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Maria Teresa GimenezGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Valeria PeriGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Karan MayaniGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
M Ángeles Montañes-GarcíaGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Ana VillalbaGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
Jesus María Hernandez RivasServicio de Hematología, Hospital Universitario de Salamanca (HUS), Salamanca, Spain.
Marina Díaz-BeyáGrupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain.
María Díez-CampeloServicio de Hematología, Hospital Universitario de Salamanca (HUS), Salamanca, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

VEXAS syndrome ('Vacuoles', 'E1 enzyme', 'X-linked', 'Autoinflammatory' and 'Somatic') is a rare autoinflammatory disorder caused by somatic mutations in the

Indexed as

Hereditary Autoinflammatory DiseasesUbiquitin-Activating EnzymesAgedHumansMaleMutationMyelodysplastic SyndromesPhenotypePrognosisRetrospective StudiesSkin Diseases, GeneticTreatment OutcomeUBA1 protein, humanUbiquitin-Activating Enzymesautoinflammatory diseaseclonal hematopoiesismyelodysplastic syndromesUBA1 geneVEXAS syndrome

Identifiers

PMID42136657
PMCPMC13168092

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.