Observational studyActa anaesthesiologica Scandinavica2026
Association of Suspected Aspiration During of Out-Of-Hospital Cardiac Arrest With Development of Early-Onset Pneumonia.
Observational study in Acta anaesthesiologica Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly-onset pneumonia is a possible complication after out-of-hospital cardiac arrest (OHCA) resuscitation. Whether or not a suspected aspiration during prehospital care is associated with the development of early-onset pneumonia has not been studied.
methodsWe conducted a single-centre prospective observational study among comatose out-of-hospital cardiac arrest survivors treated in the intensive care unit (ICU). Both prehospital emergency physicians and nurse-paramedics completed a structured survey on possible aspiration after each successful resuscitation. The primary outcome was being diagnosed with early-onset pneumonia within the first 96 h of ICU stay.
resultsA total of 55 patients were included, and 11 patients were suspected of having aspirated during their out-of-hospital cardiac arrest. Patients with suspected aspiration were younger, had a lower Charlson comorbidity index, and their out-of-hospital cardiac arrest was more often due to non-cardiac aetiology with a non-shockable primary rhythm. Patients with suspected aspiration had comparable oxygenation, ventilation, and ventilator parameters to the patients without suspected aspiration. Pneumonia findings on chest X-rays, CT imaging, and infection parameters were similar across the patient groups. Early-onset pneumonia during the first 96 h was as common in both groups (91% vs. 68%, p = 0.130). Prehospital suspicion of aspiration was not associated with early-onset pneumonia in multivariable regression analysis (odds ratio 2.8, 95% confidence interval 0.29-28).
conclusionSuspicion of aspiration during out-of-hospital cardiac arrest was not associated with early-onset pneumonia. However, this study was possibly underpowered to detect clinically relevant differences. EDITORIAL COMMENT: This study presents associations between post-cardiac arrest and resuscitation early pneumonia and suspicion of pulmonary aspiration at the time of the out of hospital cardiac arrest and first treatment. In this cohort, there did not seem to be a clear association.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.