Evidence map›Paper›PMID 42136135›Full record

ArticleChemistryOpen2026

Metal-Free, Chemoselective Reduction of Aromatic Nitro Compounds in Water at Room Temperature.

Maria Batzaki, Thomas S A Heugebaert, Christian V Stevens

Abstract read
In one paragraph

Article in ChemistryOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maria BatzakiDepartment of Green Chemistry and Technology, Faculty of Bioscience Engineering, Campus Coupure Links, Ghent University, Gent, Belgium.
Thomas S A HeugebaertDepartment of Green Chemistry and Technology, Faculty of Bioscience Engineering, Campus Coupure Links, Ghent University, Gent, Belgium.
Christian V StevensDepartment of Green Chemistry and Technology, Faculty of Bioscience Engineering, Campus Coupure Links, Ghent University, Gent, Belgium.ORCID https://orcid.org/0000-0003-4393-5327

Funding

Horizon MSCA 2021 DN 01-01 101073089
6 · The paper itself

Abstract

A metal-free, rapid, and chemoselective protocol for the nitro reduction of aromatic compounds is reported using tetrahydroxydiboron as reducing agent and 4,4'-bipyridine as organocatalyst. This method provides the transformation to aromatic amines with high functional group tolerance in good to excellent yields, under mild conditions (ambient temperature) and water as solvent.

Indexed as

aqueous medium reactionschemoselective reduction of nitroarenesgreen and sustainable chemistrymetal‐free reduction methodsroom temperature organic synthesis

Identifiers

PMID42136135
PMCPMC13176622

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.