Evidence map›Paper›PMID 42136126›Full record

ArticleTheScientificWorldJournal2026

Geographical Variation in Centella asiatica (L.) Urban: Morphological Adaptations Associated With Distinct Phytochemical Signals and Bioactivity of Extracts.

Mingle A Pistanty, Okid Parama Astirin, Soerya Dewi Marliyana, Solichatun Solichatun

Abstract read
In one paragraph

Article in TheScientificWorldJournal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mingle A PistantyDepartment of Mathematics and Science Education, Faculty of Teacher Training and Education, Cenderawasih University, Jayapura, Indonesia.ORCID https://orcid.org/0000-0002-1288-9658
Okid Parama AstirinDepartment of Biology, Faculty of Mathematics and Natural Sciences, Sebelas Maret University, Surakarta, Indonesia, uns.ac.id.ORCID https://orcid.org/0009-0002-8327-4711
Soerya Dewi MarliyanaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Sebelas Maret University, Surakarta, Indonesia, uns.ac.id.
Solichatun SolichatunDepartment of Biology, Faculty of Mathematics and Natural Sciences, Sebelas Maret University, Surakarta, Indonesia, uns.ac.id.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Centella asiatica (L.) Urban is a medicinal plant whose extract quality can vary with environmental context and associated differences in plant morphology and secondary metabolism. This study examined how geographical variation across three Indonesian agroecological regions (Kediri, Kulon Progo, and Tawangmangu) is associated with morphological variation, qualitative phytochemical profiles, and measured bioactivity of C. asiatica extracts. Comparative analyses revealed distinct region-specific morphological traits that covaried with differences in extraction yield, qualitative phytochemical signals, antioxidant capacity, and photoprotective activity. Among the tested solvent systems, ethanol consistently produced extracts with broader metabolite-class signals and higher measured bioactivity. The high-altitude Tawangmangu accession extracted with ethanol showed the lowest IC

Indexed as

CentellaPhytochemicalsPlant ExtractsTriterpenesAntioxidantsGeographyIndonesiaAntioxidantsCentella asiatica extractPhytochemicalsPlant ExtractsTriterpenesantioxidant activityCentella asiaticageographical variationmorphological adaptationphytochemical profilesun protection factor (SPF)

Identifiers

PMID42136126
PMCPMC13176621

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.