Evidence map›Paper›PMID 42135894›Full record

ReviewRenal failure2026

A review of the sirtuins family: pivotal regulators and emerging therapeutic targets in renal fibrosis.

Qiqi Deng, Chaonian Li, Jing Luo, Mengting Yin, Shilei Qian, Li Li

Abstract readReview
In one paragraph

Review in Renal failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qiqi DengDepartment of Traditional Chinese Medicine, Binhai County People's Hospital, Yancheng, Jiangsu Province, China.
Chaonian LiDepartment of Traditional Chinese Medicine, Binhai County People's Hospital, Yancheng, Jiangsu Province, China.
Jing LuoDepartment of Clinical Medical Research, Binhai County People's Hospital, Yancheng, Jiangsu Province, China.
Mengting YinDepartment of Traditional Chinese Medicine, Binhai County People's Hospital, Yancheng, Jiangsu Province, China.
Shilei QianDepartment of Urology, Binhai County People's Hospital, Yancheng, Jiangsu Province, China.
Li LiDepartment of Clinical Medical Research, Binhai County People's Hospital, Yancheng, Jiangsu Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal fibrosis represents the common pathological endpoint of chronic kidney disease (CKD) progression, yet effective therapies remain limited. The sirtuins family (SIRT1-SIRT7), NAD

Indexed as

Renal Insufficiency, ChronicSirtuinsAnimalsAutophagyFibrosisHumansInflammationOxidative StressSignal TransductionSirtuin 1Sirtuin 2SIRT1 protein, humanSIRT2 protein, humanSIRT6 protein, humanSirtuin 1Sirtuin 2Sirtuinsdeacetylaserenal fibrosisreviewSirtuinsTGF-β/smad

Identifiers

PMID42135894
PMCPMC13182182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.