Evidence map›Paper›PMID 42135666›Full record

ArticleBMC geriatrics2026

Sedentary behavior and cognitive impairment risk in older Chinese adults: effect modification by physical activity.

Zonghao Sun, Qiang Feng, Jingjing Wang, Yini Wu, Wenchao Wang, Chenhui Xiao, Xu Zhang, Chaoqun Fan

Abstract read
In one paragraph

Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zonghao SunNational Fitness and Scientific Fitness Research Center, China Institute of Sport Science, Beijing, 100061, China.
Qiang FengNational Fitness and Scientific Fitness Research Center, China Institute of Sport Science, Beijing, 100061, China.
Jingjing WangNational Fitness and Scientific Fitness Research Center, China Institute of Sport Science, Beijing, 100061, China.
Yini WuNational Fitness and Scientific Fitness Research Center, China Institute of Sport Science, Beijing, 100061, China.
Wenchao WangNational Fitness and Scientific Fitness Research Center, China Institute of Sport Science, Beijing, 100061, China.
Chenhui XiaoNational Fitness and Scientific Fitness Research Center, China Institute of Sport Science, Beijing, 100061, China.
Xu ZhangNational Fitness and Scientific Fitness Research Center, China Institute of Sport Science, Beijing, 100061, China.
Chaoqun FanNational Fitness and Scientific Fitness Research Center, China Institute of Sport Science, Beijing, 100061, China. fanchaoqun@ciss.cn.

Funding

China Institute of Sport Science Grant No. 23-21
6 · The paper itself

Abstract

backgroundBased on a nationally representative sample, this study aimed to analyze the association between sedentary behavior (SB) and cognitive impairment risk (CIR) among older Chinese adults, identify high-risk populations, and examine the effect modification of physical activity (PA) on this association.

methodsA total of 29,046 older adults aged 60-79 years were included from the 2025 China Sixth National Physical Fitness Surveillance database. SB and PA information were collected through structured questionnaires, and CIR was screened using the Ascertain Dementia 8 (AD8) scale. Multivariable logistic regression models were applied to analyze the association between SB and CIR, adjusting for confounding factors including sex, age, residential setting, educational attainment, geographic region, marital status, living arrangement, smoking status, and alcohol consumption. Stratified analyses were conducted to identify high-risk subgroups, and the effect modification by PA on the SB-CIR association was examined.

resultsThe overall CIR detection rate was 14.0% (4,075/29,046). After adjusting for confounding factors, using the 0-120 min/day SB group as the reference, the odds ratios (ORs) for CIR were 1.35 (95% CI: 1.23-1.48), 1.62 (1.47-1.79), and 1.89 (1.72-2.07) for SB of 120-180 min/day, 180-240 min/day, and ≥ 240 min/day, respectively, demonstrating a significant dose-response association (p < 0.001). The association was stronger among rural-dwelling and oldest-old (75-79 years) adults. Significant effect modification by PA on the SB-CIR association was observed (p for interaction = 0.02).

conclusionSB was significantly associated with CIR among older Chinese adults, and PA may modify the strength of this association. These findings suggest that rural-dwelling and oldest-old adults are populations warranting particular attention.

Indexed as

Cognitive DysfunctionExerciseSedentary BehaviorAgedChinaFemaleHumansMaleMiddle AgedRisk FactorsCognitive impairment riskOlder adultsPhysical activitySedentary behavior

Identifiers

PMID42135666
PMCPMC13343672

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.