Evidence map›Paper›PMID 42135659›Full record

ArticleBMC anesthesiology2026

Preoperative and intraoperative oxygen consumption in patients undergoing lung resection surgery: a retrospective study using cardiopulmonary exercise test and intraoperative data.

Chahyun Oh, Sangil Park, Sanghun Lee, Yooyoung Chong, Sung Joon Han, Min-Woong Kang, Boohwi Hong

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Article in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Chahyun Oh *Department of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea.
Sangil Park *Department of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea.
Sanghun LeeDepartment of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea.
Yooyoung ChongDepartment of Thoracic & Cardiovascular Surgery, College of Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea. yooychong@gmail.com.
Sung Joon HanDepartment of Thoracic & Cardiovascular Surgery, College of Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea.
Min-Woong KangDepartment of Thoracic & Cardiovascular Surgery, College of Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea.
Boohwi HongDepartment of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea. koho0127@cnuh.co.kr.

Funding

Chungnam National University Hospital 2024-CF-015National Research Foundation of Korea RS-2025-16068911
6 · The paper itself

Abstract

backgroundOxygen consumption (VO₂) is a core element of hemodynamic physiology and the metabolic counterpart to oxygen delivery. Modern anesthesia machines enable real-time intraoperative VO₂ estimation, yet its relationship with preoperative metabolic capacity, as characterized by cardiopulmonary exercise testing (CPET), has not been directly examined.

methodsThis study analyzed preoperative CPET and intraoperative data from adult patients ≥ 20 undergoing lung resection under general anesthesia. Intraoperative VO₂ was estimated from minute ventilation and inspired and end-tidal oxygen fractions. Preoperative and intraoperative VO₂ were summarized, and associations between baseline VO₂ and intraoperative suppression were assessed.

resultsData from 32 patients were analyzed. Preoperative VO₂ at rest, anaerobic threshold, and peak exercise were 1.6 ± 0.4, 5.1 ± 1.9, and 6.1 ± 1.7 metabolic equivalents (METs), respectively. The reduction from resting to intraoperative VO₂ (-29.0 ± 19.4%) showed a strong correlation with resting VO₂ (r = 0.770, p < 0.001). Consequently, regardless of preoperative resting VO₂, intraoperative VO₂ converged to a relatively narrow range, averaging 1.1 ± 0.2 METs.

conclusionsIn patients undergoing lung resection, intraoperative VO₂ converged to approximately 1 MET under general anesthesia, largely independent of preoperative resting metabolism. The clinical implications of this observation remain unclear and warrant investigation in larger prospective studies incorporating concurrent measurements of oxygen delivery and clinical outcomes.

Indexed as

Exercise TestLungMonitoring, IntraoperativeOxygen ConsumptionAgedAnesthesia, GeneralFemaleHumansMaleMiddle AgedRetrospective StudiesAnaerobic thresholdCardiopulmonary exercise testGeneral anesthesiaMetabolic equivalentOxygen consumptionPulmonary surgical proceduresResting metabolic rate

Identifiers

PMID42135659
PMCPMC13348590

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.