Evidence map›Paper›PMID 42135566›Full record

SynthesisTechniques in coloproctology2026

The role of artificial intelligence in adenoma detection during colonoscopy: a systematic review and meta-analysis of randomized controlled trials-Artificial intelligence and adenoma detection.

Alimohammad Bananzadeh, Mahshid Bahadori, Seyed Mohammad Kazem Tadayon, Sara Shojaei-Zarghani, Seyed Vahid Hosseini

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Techniques in coloproctology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alimohammad Bananzadeh *Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID http://orcid.org/0000-0003-1116-2294
Mahshid Bahadori *Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Seyed Mohammad Kazem TadayonColorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Sara Shojaei-ZarghaniColorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. shojaeisara@ymail.com.ORCID http://orcid.org/0000-0001-8479-065X
Seyed Vahid HosseiniColorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColonoscopy is the gold standard for colorectal cancer screening; however, it is limited by a substantial adenoma miss rate. We aimed to provide an updated and comprehensive synthesis of evidence from randomized controlled trials (RCTs) on the efficacy of artificial intelligence (AI)-assisted versus conventional colonoscopy in detecting colorectal adenomas.

methodsA systematic literature search of PubMed, Scopus, and Web of Science was conducted up to 6 May 2025. Primary outcomes included the adenoma detection rate (ADR), adenomas per colonoscopy (APC), sessile serrated lesion detection rate (SSLDR), SSLs per colonoscopy (SSLPC), adenoma miss rate (AMR), and SSL miss rate (SSLMR). Pooled risk ratios (RR) and mean differences (MD) with 95% confidence intervals (CIs) were calculated using a random-effects model.

resultsA total of 46 RCTs, involving 37,206 participants, were included. AI-assisted colonoscopy significantly increased ADR (RR = 1.22, 95% CI: 1.17-1.27, I

conclusionsThis comprehensive meta-analysis confirms that AI-assisted colonoscopy significantly improves the detection of conventional adenomas and reduces miss rates. While it also improves the SSLDR, its effect on reducing their miss rate remains inconclusive.

Indexed as

AdenomaArtificial IntelligenceColonoscopyColorectal NeoplasmsEarly Detection of CancerHumansRandomized Controlled Trials as TopicArtificial intelligenceColonoscopyMachine learningMeta-analysis as topicNeoplasms

Identifiers

PMID42135566
PMCPMC13341714

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.