Evidence map›Paper›PMID 42135547›Full record

Observational studyAnnals of surgical oncology2026

Sentinel Lymph Node Positivity and Utility of Frozen Section Diagnosis following Neoadjuvant Therapy in Patients with Clinically Node-Negative, Hormone Receptor-Positive, HER2-Negative Breast Cancer.

Kerollos Nashat Wanis, Rrita Krasniqi, Susie X Sun, Erika Resetkova, Rosa F Hwang, Kelly K Hunt, Rosalind P Candelaria, Lei Huo, Puneet Singh

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kerollos Nashat Wanis *Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. kwanis@mdanderson.org.
Rrita Krasniqi *Department of Pathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, 77030, TX, USA.
Susie X SunDepartment of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Erika ResetkovaDepartment of Pathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, 77030, TX, USA.
Rosa F HwangDepartment of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Kelly K HuntDepartment of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Rosalind P CandelariaDepartment of Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Lei HuoDepartment of Pathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, 77030, TX, USA. LeiHuo@mdanderson.org.
Puneet SinghDepartment of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFrozen section evaluation can be used for intraoperative diagnosis of sentinel lymph node (SLN) metastases. When completion axillary lymph node dissection is planned owing to positive SLNs following neoadjuvant chemotherapy (NACT), frozen section may be considered to facilitate completion of axillary surgery at the index operation. The utility of intraoperative SLN assessment with frozen section in patients with hormone receptor-positive (HR PATIENTS AND

methodsWe conducted a single-institution observational cohort study including patients with noninflammatory, cN0, HR

resultsOf 145 eligible patients, 47 (32.4%; 95% confidence interval [CI]: 24.9, 40.7) had SLN metastases. Positive SLNs were more frequent among those with ER

conclusionsIn patients with cN0 HR

Indexed as

Breast NeoplasmsFrozen SectionsNeoadjuvant TherapySentinel Lymph NodeAdultAgedBiomarkers, TumorErb-b2 Receptor Tyrosine KinasesFemaleFollow-Up StudiesHumansLymphatic MetastasisMiddle AgedPrognosisReceptors, EstrogenReceptors, ProgesteroneBiomarkers, TumorERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesReceptors, EstrogenReceptors, Progesterone

Identifiers

PMID42135547
PMCPMC13337608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.