Evidence map›Paper›PMID 42135541›Full record

ArticleAnnals of surgical oncology2026

Identifying Predictors of Delayed Ambulation After Minimally Invasive Gynecologic Oncology Surgery.

Diamond Gallimore, Atipa Nitayamekin, Emily A Vertosick, Maricka Bennett, Joanna Serafin, Andrew Vickers, Daniel Stein, Jennifer J Mueller, Sigrid V Carlsson, Melissa Assel and 1 more

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Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Diamond Gallimore *School of Medicine, University of South Carolina, Columbia, SC, USA.
Atipa Nitayamekin *Department of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Emily A VertosickDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Maricka BennettSchool of Medicine, Tufts University, Boston, MA, USA.
Joanna SerafinDepartment of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Andrew VickersDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Daniel SteinDepartment of Digital Informatics and Digital Technology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jennifer J MuellerDepartment of Surgery, Gynecology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sigrid V CarlssonDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Melissa AsselDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Anoushka M AfonsoDepartment of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, NY, USA. afonsoa@mskcc.org.

Funding

NCI NIH HHS P30-CA008748
6 · The paper itself

Abstract

backgroundEarly ambulation is a cornerstone of enhanced recovery after surgery (ERAS) programs, reducing pulmonary and thromboembolic complications. Gynecologic oncology patients are at particular risk, yet factors of delayed ambulation remain underexplored. Using objective monitoring from a real-time locating system (RTLS), this study examined patient and procedural predictors of delayed ambulation, defined as occurring on the first postoperative day.

methodsThe study retrospectively reviewed 2545 robot-assisted hysterectomies performed with the patient under general anesthesia between 2016 and 2022 at a high-volume, free-standing ambulatory surgical center. After exclusions, 1716 cases were analyzed. Ambulation was tracked using RTLS. Logistic regression with surgery end time (plus non-linear terms) was used to evaluate predictors of next-day ambulation, including age, body mass index, intravenous fluid, opioid use, American Society of Anesthesiologist class, postoperative nausea and vomiting (PONV) risk score, operative time, blood loss, and perioperative antiemetic use.

resultsThe median time from recovery room arrival to first ambulation was 4.8 h (interquartile range, 3.7-6.4 h), with 11 % first ambulation the next day. Later surgery end time and longer operative time were significantly associated with delayed ambulation. Patients with the highest PONV risk score (Apfel 4) had double the odds of next-day ambulation compared with PONV risk ≤3 (odds ratio 1.94; 95 % confidence interval 1.31-2.86; p = 0.001). This correlation persisted after adjustment for preoperative aprepitant and intraoperative dexamethasone or ondansetron.

conclusionsHigher PONV risk score predicted increased odds of next-day ambulation, independently of antiemetic prophylaxis. To facilitate ambulation within the same day of surgery, patients with high PONV risk scores may be scheduled earlier in the day.

Indexed as

Early AmbulationGenital Neoplasms, FemaleGynecologic Surgical ProceduresMinimally Invasive Surgical ProceduresPostoperative ComplicationsPostoperative Nausea and VomitingWalkingAgedFemaleFollow-Up StudiesHumansMiddle AgedPrognosisRetrospective StudiesRisk FactorsAmbulationAmbulatory gynecologic surgeryApfel scoreEnhanced recovery after surgeryPostoperative nausea and vomiting

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.