Evidence map›Paper›PMID 42135463›Full record

ArticleNPJ digital medicine2026

Randomized trial of electronic health record implemented AI risk prediction in kidney transplant care.

Bilgin Osmanodja, Jakob Joachim Spencker, Ömer Ege Ömeroğlu, Zeineb Sassi, Roland Roller, Sascha Vu-Eickmann, Hannah Thomas, Aljoscha Burchardt, Michael Hahn, Tabea Ott and 4 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bilgin OsmanodjaDepartment of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany. bilgin.osmanodja@charite.de.
Jakob Joachim SpenckerDepartment of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Ömer Ege ÖmeroğluDepartment of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Zeineb SassiDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.
Roland RollerGerman Research Center for Artificial Intelligence, Berlin, Germany.
Sascha Vu-EickmannInstitute of General Practice, University Hospital Regensburg, Regensburg, Germany.
Hannah ThomasDepartment of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Aljoscha BurchardtGerman Research Center for Artificial Intelligence, Berlin, Germany.
Michael HahnChair of Systematic Theology II (Ethics), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Tabea OttDepartment of Systematic Theology and the Study of Religions, University of Vienna, Vienna, Austria.
Peter DabrockChair of Systematic Theology II (Ethics), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Sebastian MöllerGerman Research Center for Artificial Intelligence, Berlin, Germany.
Klemens BuddeDepartment of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Anne HerrmannDepartment of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.

Funding

Bundesministerium für Forschung, Technologie und Raumfahrt 01GP2202ABundesministerium für Forschung, Technologie und Raumfahrt 01GP2202BBundesministerium für Forschung, Technologie und Raumfahrt 01GP2202CBundesministerium für Forschung, Technologie und Raumfahrt 01GP2202D
6 · The paper itself

Abstract

Artificial intelligence (AI)-based risk prediction is increasingly implemented in clinical care, but randomized evidence on communication and shared decision-making (SDM) outcomes is limited. In the single-center PRIMA-AI trial, 76 kidney transplant recipients with estimated glomerular filtration rate <30 mL/min/1.73 m² were randomized 1:1 to usual care or usual care plus an electronic health record (EHR)-integrated machine-learning model predicting 1-year graft loss risk. The primary outcome was patient-reported conversations about treatment options after graft loss during 12 months. Conversation frequency did not differ between groups (intervention 14/36 [39%] vs control 16/40 [40%]; chi-square p = 1.00). No significant between-group differences were observed for secondary clinical, SDM-related, relationship, or distress outcomes. Post-study user feedback suggested low and variable tool uptake with workflow barriers. Passive EHR availability of AI risk estimates did not improve communication or SDM-related outcomes. Future interventions should strengthen workflow integration and directly support SDM. Trial Registration: ClinicalTrials.gov number, NCT0605651, registered 2023-09-21.

Identifiers

PMID42135463
PMCPMC13176338

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.