Evidence map›Paper›PMID 42134788›Full record

ReviewImmunology and cell biology2026

Highlights of 2025: advances in germinal centers.

Louise Mc Webb, Michelle A Linterman

Abstract readReview
In one paragraph

Review in Immunology and cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. ICB Special Feature: Highlights of 2025.Immunology and cell biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Louise Mc WebbBabraham Institute, Cambridge, UK.ORCID https://orcid.org/0000-0003-3417-1484
Michelle A LintermanBabraham Institute, Cambridge, UK.ORCID https://orcid.org/0000-0001-6047-1996

Funding

Biotechnology and Biological Sciences Research Council BBS/E/B/000C0427Lister Institute of Preventive Medicine
6 · The paper itself

Abstract

The germinal center (GC) is the engine room of the humoral immune response, driving the evolution of B cells into memory and long-lived plasma cells that can protect against (re)infection. Understanding GC biology remains a key research focus for promoting lifelong health. In this annual update, we highlight several influential studies on GC biology published in 2025 (Fig. 1). Space constraints prevent us from discussing in depth all published work.

Indexed as

B-LymphocytesGerminal CenterAnimalsHumansImmunity, HumoralB lymphocytesgerminal centerT cellsT follicular helper cells

Identifiers

PMID42134788
PMCPMC13331530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.